Research Scientist J.Lee Lab

Mass General BrighamBoston, MA
Hybrid

About The Position

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Summer: Drives research projects scientifically and determines the course of research as evidenced by leadership, obtaining funding, writing, or other recognition. May not necessarily receive independent resources; however, their contribution is essential to the conceptual/scientific success of the project.

Requirements

  • Doctorate Related Field of Study required
  • Previous Research experience (inclusive of graduate and postdoctoral experience) 5-7 years required
  • Excellent research skills.
  • Demonstrated evidence of specific scientific competence in field.
  • Demonstrated broad knowledge of field.
  • Evidence of potential for scientific creativity and original thought.
  • Able to exercise independent judgment and leadership.
  • Ability to contribute to publications.

Responsibilities

  • Design and perform genetic association analysis.
  • Design, plan, and execute cell-based, biochemical, and in vivo experiments necessary to validate target genes for therapeutic discovery.
  • Maintain cell lines and isolate primary cells for use in cell-based assays.
  • Work with informatics and computational scientists to integrate and interpret screening and functional genomic data sets.
  • Perform detailed characterization and cellular mechanism of action studies of chemically optimized compounds.
  • Perform mouse genetic linkage analysis to define genes affecting genome instability
  • Work with team to design and execute research plans to ensure that critical project requirements, timelines, and deliverables are met.
  • Troubleshoot and solve scientific problems independently.
  • Identify, investigate and implement new technologies based on scientific needs.
  • Effectively present results in cross-functional project teams.
  • Design, execute, and interpret research experiments.
  • Train investigators in techniques relating to small animal surgery, molecular biology, and vector construction.
  • Investigates, creates and develops new methods and technologies for research advancements
  • Assist in laboratory management.
  • Contribute to scientific literature and present research at scientific forums

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What This Job Offers

Job Type

Full-time

Career Level

Senior

Education Level

Ph.D. or professional degree

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