Research Scientist/Engineer 3, Zhu Lab
About The Position
The Research Scientist/Engineer 3 (RS/E 3) in the Zhu Laboratory leverages state-of-the-art microphysiological systems, imaging technologies, and single cell RNA sequencing and spatial transcriptomics to study host immune responses against chronic viral infection in human skin. The RS/E 3 performs various in situ assays and directs students and other trainees to ensure successful completion of the research project. Additionally, the RS/E 3 performs data analysis, generates summary reports, and contributes to manuscript preparation and grant application. This is a full-time day shift position located at the Fred Hutch Cancer Research Center (1100 Eastlake Building). The specific work schedule will be discussed with the hiring manager.
Requirements
- Bachelor’s degree in Biological Sciences or related field.
- At least four years of experience in the field of mucosal immunology, viral-host interactions, antigen-specific T cell responses,
- Possesses the knowledge to build microphysiological devices, such as “skin-on-chip” platform for virological and immunological evaluation.
- The ability to generate, process and analyze high-parameter, high content multiplex imaging data.
- Strong written and communication skills.
- Ability to solve problems and troubleshoot.
Nice To Haves
- Working experience in immune responses to herpes simplex virus infection is highly desired.
- Highly skilled in laboratory benchwork, such as building skin organoid and microphysiological devices.
- Hands on experience in microfluidics.
Responsibilities
- Perform high level research and engineering work, analyze data, compile results and draft reports for incoming research awards and/or contracts.
- Perform wet experiments and digital image data analysis of patient tissue specimens.
- Generate, process and analyze high-parameter multiplex immunofluorescence imaging data.
- Process biopsy tissues, perform library constructions and quality control and generate final products for single-cell RNA sequencing.
- Perform work accurately, precisely and meet completion deadlines.
- Analyze experimental data and recommend modifications and follow-up experiments.
- Review the scientific processes, conduct statistical analysis; present data using graphs and figures.
- Develop and optimize research protocols and methodologies.
- Maintain accurate, secure, and HIPAA-compliant records.
- Manage and lead research projects of small to moderate size and scope.
- Organize, prioritize, and coordinate project activities to meet timelines and milestones.
- Identify long and short-term goals; initiate research program/projects.
- Assess feasibility of study goals and provide technical expertise during project development.
- Collaborate with research teams to develop analytical pipelines for complex immune and spatial biology datasets.
- Contribute data analyses and technical content for grant applications, scientific manuscripts, presentations, and reports.
- Conduct literature reviews to support project planning and development.
- Provide technical guidance and feedback to project collaborators and team members.
- Participate in laboratory maintenance, equipment management, and inventory control.
- Maintain documentation and document-control systems.
- Accommodate schedule changes and support team priorities.
- Assist with continuity of research operations by supporting colleagues' experiments as needed.
- Participate in team meetings and collaborative activities.
- Perform other related duties as assigned to support laboratory objectives.
Benefits
- outstanding benefits
- opportunities for professional growth
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What This Job Offers
Job Type
Full-time
Career Level
Senior
