Research Lab Technician I

Mass General Brigham•Boston, MA

3d•Onsite

About The Position

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. We are seeking a scientifically motivated individual for a pre-Ph.D./M.S. research opportunity within the MGH Hepatology research environment. This is a one-year appointment with the possibility of a one-to-two-year extension, emphasizing training and the acquisition of advanced biological and computational skills. The successful candidate will join a highly collaborative team, work under the direct mentorship of Principal Investigator Prof. Nadia Alatrakchi and learn essential skills for a future career in science. Our laboratory studies immune cell populations in the setting of human disease, with a particular focus on innate immunity. We utilize in vitro and in vivo assays, single-cell RNA sequencing, and spatial transcriptomics to investigate the liver microenvironment and peripheral blood of patients and animal models of fatty liver disease. Additionally, we study chronic viral hepatitis pathologies, including HBV and HIV coinfections. Our goal is to uncover the molecular mechanisms driving disease progression to develop more effective therapeutic strategies and predictive diagnostic tests.

Requirements

Bachelor's Degree in a Related Field of Study required.
Prior laboratory experience, either through academic coursework, internships, or employment (1-2 years preferred).
Strong theoretical and practical knowledge of laboratory techniques and procedures.
Familiarity with common laboratory equipment and instruments used in research experiments.
Proficiency in data collection, analysis, and scientific software tools.
Excellent attention to detail, organizational skills, and the ability to multitask and prioritize tasks effectively.
Strong problem-solving skills and the ability to troubleshoot technical issues.
Excellent written and verbal communication skills to effectively convey experimental procedures, results, and challenges.

Nice To Haves

1-2 years preferred experience

Responsibilities

Utilize in vitro and in vivo assays, single-cell RNA sequencing, and spatial transcriptomics to investigate the liver microenvironment and peripheral blood of patients and animal models of fatty liver disease.
Study chronic viral hepatitis pathologies, including HBV and HIV coinfections.
Uncover the molecular mechanisms driving disease progression to develop more effective therapeutic strategies and predictive diagnostic tests.