Research Lab Tech - Lagier-Tourenne Lab

Mass General Brigham•Boston, MA

2d•$21 - $29•Onsite

About The Position

The Research Lab Tech will join the Lagier-Tourenne Lab’s research into disease mechanisms and therapeutic strategies for amyotrophic lateral sclerosis and dementia. Under minimal supervision from the Principal Investigator and other researchers, the role supports laboratory operations and participates actively in scientific projects and lab meetings. Duties include ordering common supplies, maintaining equipment, establishing health and safety procedures, and developing protocols and standard operating procedures. The technician conducts experiments, analyzes results, and contributes to manuscript preparation. The position may be hired at the Tech I or Tech II level based on experience and skillset. The role includes DNA and RNA purification, quantitative PCR, gel electrophoresis, Western blots, DNA cloning, immunostaining, high-throughput sequencing, CRISPR/Cas9 editing, and lentiviral and mammalian cell culture, including iPSC-derived neurons. Mouse handling and mouse histology experience is preferred but not required. The technician also prepares and handles samples, reagents, and solutions; maintains and troubleshoots equipment; records and analyzes experimental data; and assists with interpretation and presentation of findings. The role requires attention to detail, independent work under minimal supervision, strong communication, and effective teamwork.

Requirements

Bachelor's degree in a related field; experience may be accepted in lieu of a degree.
Prior laboratory experience through academic coursework, internships, or employment; 1–2 years preferred.
Strong theoretical and practical knowledge of laboratory techniques and procedures.
Familiarity with common laboratory research equipment and instruments.
Proficiency in data collection, analysis, and scientific software tools.
Excellent attention to detail and organizational skills, with the ability to multitask and prioritize effectively.
Strong problem-solving skills and ability to troubleshoot technical issues.
Excellent written and verbal communication skills.
Ability to work independently under minimal supervision and as part of a team.
Candidates completing a bachelor's degree have a six-month grace period from hire to provide degree equivalency verification, or up to one year if starting per diem.

Nice To Haves

Experience with mouse handling and mouse histology is preferred but not required.

Responsibilities

Order common laboratory supplies and support laboratory organization.
Maintain laboratory equipment and perform routine calibration and troubleshooting.
Establish procedures to comply with health and safety regulations.
Develop laboratory protocols and standard operating procedures.
Perform laboratory experiments following established protocols and procedures.
Prepare and handle samples, reagents, and solutions accurately and safely.
Conduct experiments including DNA and RNA purification, quantitative PCR, gel electrophoresis, Western blots, DNA cloning, immunostaining, high-throughput sequencing, CRISPR/Cas9 editing, and lentiviral and mammalian cell culture, including iPSC-derived neurons.
Record experimental data and maintain organized records of procedures, protocols, and results.
Compile and analyze data using appropriate statistical and analytical methods.
Assist with data interpretation and presentation, contributing to research findings and reports.
Participate in scientific projects and laboratory meetings.
Contribute to preparation of manuscripts.