Research Lab Tech

Mass General Brigham•Boston, MA

1d•Onsite

About The Position

A research lab within Brigham and Women’s Cardiovascular Medicine division is looking for a highly motivated technical research assistant I. The lab uses both in vitro (human ESC/iPSC) and in vivo (zebrafish) techniques to model various cardiovascular disorders, including atrial fibrillation, hypertrophic cardiomyopathy, atherosclerosis, and arteriovenous malformations. By integrating transcriptional, (epi)genetic, metabolic, and phenotypic profiling at whole organism, issue, and single cell-level, the lab aims to understand the earliest molecular events characterizing disease onset, follow-up their dynamic changes over time, and to identify disease biomarkers. The lab also uses these zebrafish models to expedite drug discovery in cardiovascular medicine.

Requirements

BA/BS in biology, chemistry, or closely related field
0-1 years experience

Nice To Haves

Prior laboratory research experience.
Prior experience working with zebrafish.

Responsibilities

Perform a variety of laboratory experiments under general supervision. These will include molecular and cellular techniques such as PCR, microdissection, western blotting, immunofluorescence microscopy, DNA purification, and quantitative RT-PCR.
Help to maintain zebrafish colonies.
Preparation and maintenance of cell and tissue cultures.
Preparation of laboratory reagents, chemicals, instruments, and equipment.
Chemical informatics.
Collaborate with a team of research assistants and post docs to meet project goals in a fast-paced and dynamic wet lab setting.
Help to establish new and modify existing research techniques.
Help to coordinate with core facilities and collaborating labs.
Perform time-lapse microscopy and automated image processing.
Meticulously record procedures and results in an electronic lab notebook; follow the required safe practices and comply with institutional policies and procedures.
Discusses progress of work regularly with supervisors.
May be asked to work some nights and weekends when needed (overtime will apply).
All other duties, as assigned