Research Lab Tech I

Mass General Brigham•Boston, MA
•Onsite

About The Position

The Laboratory Research Technician I assists a Principal Investigator with basic science research in the molecular genetics of brain cancer. Under the supervision of the project head and laboratory PI, the technician supports research projects by setting up and conducting laboratory tests and experiments using established methods, procedures, and techniques in a neurosurgery tumor research laboratory. The role includes performing and adapting research protocols, troubleshooting experimental methods and equipment, conducting molecular biology procedures, assisting with mouse experiments, collecting and presenting research data, and maintaining laboratory operations, supplies, records, and equipment. The technician also participates in laboratory meetings, presents research findings, reviews scientific literature, and provides technical guidance to others as needed.

Requirements

  • Bachelor's degree with a major in a biological science, or an equivalent combination of education and experience.
  • Ability to work independently and as a team member, using good judgment, organization, attention to detail, and time-management skills.
  • Ability to manage laboratory inventory and records.
  • Problem-solving ability using analytical skills and technical knowledge.
  • Ability to use data-management programs appropriately.
  • Ability and willingness to work safely with or be exposed to hazardous materials, including radioactive materials, infectious materials, and hazardous chemicals.
  • Ability to sustain long periods of work at a desk, computer, or laboratory bench.
  • Ability to lift and install equipment, such as centrifuge rotors, for certain experiments.
  • Good eye-hand coordination, manual dexterity, and visual acuity to complete tasks and analyze results.
  • Clear, effective oral and written communication and English proficiency for research reports, seminars, teaching, and discussions.
  • Good math, library, documentation, time-management, and organizational skills for routine duties.
  • Knowledge of computers and software applications, including spreadsheets.

Nice To Haves

  • Laboratory-based coursework is preferred.
  • Some laboratory experience beyond school laboratory experience is desirable but not required.
  • Undergraduate coursework or completed projects may be considered related experience and credited upon hire.
  • Competence and knowledge in several laboratory methods, including molecular biology, protein chemistry, immunohistochemistry, and biochemistry.

Responsibilities

  • Assist with research experiments and projects under the supervision of the project head and laboratory PI.
  • Perform laboratory work, including basic design and modification of protocols and execution of non-routine experiments.
  • Identify and troubleshoot problems with experimental methods, procedures, techniques, equipment, and facilities; correct them or recommend solutions.
  • Develop and implement new or modified research methods, procedures, and techniques, and incorporate new procedures into laboratory protocols.
  • Perform molecular biology techniques, including PCR amplification, gel electrophoresis, transfection, plasmid DNA purification, and sterile cell culture.
  • Follow laboratory safety requirements, including appropriate disposal of general, chemical, and hazardous waste.
  • Assist with mouse experiments, including administering drugs and monitoring body condition.
  • Maintain detailed, organized laboratory notebooks documenting research procedures and results so that others can understand and repeat the work.
  • Prepare graphs, charts, and scientific posters to present data at laboratory meetings and national meetings.
  • Participate in laboratory meetings and give oral presentations on research findings and summaries of research papers.
  • Continue learning by reading and researching relevant scientific literature.
  • Oversee day-to-day laboratory management, including proper use, maintenance, and availability of equipment and supplies.
  • Order and maintain general and specialized laboratory supplies and reagents.
  • Organize and maintain laboratory stocks, including tumor and normal blood samples, tissue culture cells, plasmid DNAs, restriction enzymes, and other relevant reagents.
  • Unpack, place, and document receipt of general and specialized supplies.
  • Maintain invoice records, track grant spending, and address incorrect charges.
  • Instruct others in laboratory methods, procedures, and techniques and provide technical guidance and direction as needed.
  • Locate manufacturers and suppliers for laboratory equipment.

Benefits

  • Competitive base pay
  • Comprehensive benefits
  • Career advancement opportunities
  • Differentials, premiums, and bonuses as applicable
  • Recognition programs designed to celebrate contributions and support professional growth
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