Research Fellow

Mass General Brigham•Boston, MA

23h•$71,750 - $81,179•Onsite

About The Position

The Koo Laboratory in the Division of Infectious Diseases at Brigham and Women’s Hospital and Harvard Medical School seeks a motivated postdoctoral Research Fellow to contribute to collaborative research on diagnostic approaches for infections in immunocompromised hosts and the epidemiology and pathophysiology of opportunistic pathogens, especially fungi. The fellow will work under the guidance and mentorship of Dr. Sophia Koo with the Principal Investigator, collaborating faculty, research scientists, postdoctoral fellows, research assistants, and other laboratory members. The appointment will be at Mass General Brigham and Harvard Medical School. The role involves designing, conducting, and interpreting research; learning and applying molecular genomics methods, including single-cell RNA sequencing and spatial transcriptomics; maintaining murine models and processing tissues; and using advanced analytical chemistry to characterize breath volatile metabolites in patients with bacterial, viral, and fungal pneumonias. The fellow will also analyze mass spectroscopic and differential mobility spectroscopic data, document experiments, develop research methods, prepare reports and manuscripts, and contribute to research presentations. The position includes training and oversight of research assistants and students, as well as troubleshooting specialized techniques. Work is onsite in the Thorn Research Building on the Brigham and Women’s Hospital main campus in Boston, Massachusetts. The stated compensation range is $71,750–$81,179, with compensation informed by experience and organizational guidelines.

Requirements

A doctoral degree; the ideal candidate will have received or expect soon to receive an MD or PhD in a relevant biological field.
Recent MD or PhD graduate.
At least 1 year of experience in a research-related field.
Excellent English verbal and written communication skills.
Ability to work independently and as part of a team.
Interest in learning and troubleshooting new molecular biology techniques.
Familiarity with animal modeling of disease.
Excellent organizational, communication, and interpersonal skills.
Ability to supervise and train staff effectively.
Ability to prioritize tasks, set deadlines, and adapt to shifting priorities and laboratory needs.

Responsibilities

Design, execute, and interpret research experiments.
Learn and apply molecular genomics techniques, including single-cell RNA sequencing, spatial transcriptomics, and other methods.
Maintain murine models and process murine tissues for detailed evaluation.
Use advanced analytical chemistry techniques to define breath volatile metabolite profiles of patients with bacterial, viral, and fungal pneumonias.
Analyze mass spectroscopic and differential mobility spectroscopic data from laboratory experiments.
Maintain detailed records of experiments in a laboratory notebook.
Follow detailed protocols independently while collaborating with laboratory members.
Assist in training research assistants and postdoctoral fellows.
Troubleshoot problems and instruct others in specialized techniques.
Investigate, create, and develop methods and technologies to advance research.
Prepare written data reports, including methodology, figures, and written study descriptions for manuscripts or progress reports.
Contribute to research presentations at local, national, and international meetings.
Oversee and train research assistants and students participating in projects, and assist with experimental design and implementation.
Organize or draft material for research papers, manuscripts, and other publication or presentation documents.