RTP Research Fellow-LS-Dr Kun Ling-BMB

Mayo Clinic • Rochester, MN

3d • Onsite

About The Position

This position opens for a project focused on comprehending the pathogenesis of polycystic kidney disease, the #1 monogenic human disease leading to kidney failure and death. We integrate cultured cell lines, organoids, and animal models to understand how primary cilia regulate the formation of kidney cysts during development and aging. We welcome individuals who are highly curious to molecular mechanisms underlying human diseases and highly motivated and committed to explorative mechanistic research. A Research Fellow position in Life Sciences (LS) will require knowledge of either clinical-based research or laboratory-based research often obtained from a postdoctoral program. A Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars, Research Scholars, Professors, Specialists, and Student Interns sponsored by Mayo Clinic.

Requirements

• Ph.D., M.D., or equivalent doctoral degree in a field deemed relevant by the program.
• Completed no more than one prior postdoctoral fellowship, at Mayo Clinic or elsewhere.
• Knowledge of either clinical-based research or laboratory-based research.
• Common molecular and cellular techniques, including molecular cloning, mutagenesis, cell culture and transfection, and immunoblotting.
• Proof of English proficiency is required for J-1 Short-Term Scholars, Research Scholars, Professors, Specialists, and Student Interns sponsored by Mayo Clinic.

Nice To Haves

• Experience on recombinant protein expression and pull-down assays.
• Familiarity with various microscope imaging techniques especially immunofluorescence microscopy.
• Highly curious to molecular mechanisms underlying human diseases.
• Highly motivated and committed to explorative mechanistic research.

Responsibilities

• Integrate cultured cell lines, organoids, and animal models to understand how primary cilia regulate the formation of kidney cysts during development and aging.
• Conduct common molecular and cellular techniques, including molecular cloning, mutagenesis, cell culture and transfection, and immunoblotting.
• Perform recombinant protein expression and pull-down assays.
• Utilize various microscope imaging techniques, especially immunofluorescence microscopy.
• Engage in proteomics studies.
• Investigate disease phenotype in established mouse models using MRI imaging and histological analyses.
• Collaborate with researchers and physicians at the Mayo Clinic Translational PKD Center.
• Utilize research tools and technical services available at the PKD Center, including patient samples and disease models.
• Develop independent problem-solving abilities critical for research.
• Engage in teamwork and collaboration.
• Train in the research program of a Mayo Clinic principal investigator.
• Demonstrate potential for research as evidenced by training and peer-reviewed publications.
• Become competitive for national research grants.

Benefits

• Training and education in research.
• Full access to research tools and state-of-the-art technical services available at the PKD Center.
• Access to patient samples and disease models for pre-clinical studies.
• Supportive environment to promote personal growth.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree