Research Bioinformatician I - Bottini Lab - Kao Autoimmunity Institute
About The Position
The Kao Autoimmunity Institute (KAI) is seeking a Research Bioinformatician I to join the dynamic team of Principal Investigator, Nunzio Bottini, MD, PhD. The Bottini Lab focuses on studying the pathogenesis of systemic autoimmunity, particularly scleroderma and rheumatoid arthritis, with the goal of identifying more effective and personalized treatment options that minimize generalized immunosuppression. The Research Bioinformatician I will be responsible for general bioinformatics analysis and software support for omics-related projects. This role involves managing omic data, including loading and querying from databases and public repositories, transforming and merging multilevel omic data, and assisting in the development and maintenance of software pipelines for genome sequencing. The incumbent will also perform daily bioinformatics data analysis, preliminary interpretation of data, and report generation for potential publications.
Requirements
- Bachelor’s Degree in Computer Science, Electrical Engineering, Computational Biology, Bioinformatics, or relevant fields (e.g., Biology with strong quantitative training, Biostatistics with concentration in Bioinformatics) is required.
- Proficiency with C/C++, Java, Perl, python, and the Unix (Linux) environment.
- Experience in manipulating, analyzing, and annotating very large genomic (e.g. NGS) data sets, both in exploratory and pipelined fashions is highly preferred.
Nice To Haves
- Experience in a research environment is highly preferred.
- Background and work knowledge in algorithms, scientific computing, and machine learning or statistics is preferred.
Responsibilities
- Perform general bioinformatics analysis and software support for projects involving omics.
- Manage omic data including loading and querying data from database systems and public repositories.
- Transform and merge multilevel omic data into user-friendly formats.
- Assist in the development, testing, and maintenance of modular software pipelines for genome sequencing.
- Provide daily bioinformatics data analysis.
- Perform preliminary interpretation of the data.
- Generate reports of the results for possible publications.
- Responsible for data analysis and software compilations including next generation sequence alignment, polymorphism identification, expression analysis, and visualization tools and browsers.
- Summarize data analyses results in a format suitable for the first draft of written reports, and make preliminary interpretations of the data.
- Assist with assembly, annotation, metagenomic analysis, and genotyping using high-throughput sequencing platforms including 454, Illumina, and Pacific Biosciences.
- Manage and redefine data to the necessary formats.
- Help to identify, evaluate, and incorporate relevant algorithms and software pipelines by reviewing pertinent literature in bioinformatics and computational biology.
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
