About The Position

Addition Therapeutics is seeking a researcher with experience in T cell engineering and gene editing, either in industry or an academic setting. This individual would have experience in both primary lymphocyte/PBMC culture and assays required to characterize edited T cells.

Requirements

  • Bachelors Degree in Molecular and Cell Biology, Bioengineering, Immunology, or related fields with 3+ years experience engineering T cells in industry or academia.
  • Experience in primary human T cell and PBMC culture and engineering.
  • T cell functional assays (e.g. cytotoxicity, exhaustion, activation)
  • Experience in multi-color flow cytometry, DNA and RNA readout methods (ddPCR, RT-PCR, etc), and culture of cell lines.
  • Hands-on experience with in vivo models of CAR T cell efficacy and safety studies
  • Organized, motivated, and disciplined when it comes to hands-on work in the lab
  • Excellent oral and written communication skills
  • Thrives in a fast-moving, results-oriented startup environment
  • Flexible, cooperative, can-do attitude

Nice To Haves

  • Experience in non-viral gene delivery
  • RNA delivery and expression of transgenes
  • Experience in RNA synthesis and purification by in vitro transcription

Responsibilities

  • Execution of experiments involving lymphocyte engineering, gene editing, immunology, synthetic biology, molecular biology, and cell biology.
  • Collaborating on team projects.
  • Communicating, documenting, and presenting work.
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