About The Position

Abalone Bio is seeking a collaborative and highly motivated Research Associate or Senior Research Associate to join their team to support screening and characterization of antibodies. The successful candidate will perform experiments to produce and assess the function and developability of antibody drug candidates. This is an opportunity to play a role in discovering and developing rare functional antibody drugs for previously untreatable diseases.

Requirements

  • BS/BA or MS degree in molecular biology, microbiology, biochemistry, immunology or a related field
  • 3+ years of experience in biotechnology or pharmaceutical industry working with large biomolecules, preferably antibodies
  • Mammalian cell culture using sterile technique
  • Cell-based assays (HTRF, ELISA etc) using 96- and 384-well formats
  • Molecular biology techniques including PCR, gibson assembly, bacterial transformation, DNA purification
  • Strong communication skills
  • Excellent organizational and time management skills
  • Flexibility and ability to quickly learn new skills and knowledge on the job

Nice To Haves

  • Working knowledge of GPCR biology and HTRF assays to assess GPCR signaling
  • Experience in protein production and purification using mammalian cell cultures
  • Experience with making stable mammalian cell lines for assays
  • Working knowledge of data analysis using Graphpad Prism

Responsibilities

  • Execute cell based and biochemical assays to assess the antibody function using a variety of 96- and 384-well plate formats
  • Characterize antibodies for downstream developability including aggregation and stability
  • Create and maintain mammalian cell lines for use in assays
  • Execute molecular and biochemical techniques including cloning, expressing and purifying antibodies for protein production
  • Analyze scientific data and present results to project teams
  • Maintain accurate and thorough records

Benefits

  • Competitive salary (anticipated range: $75,000 - $110,000/yr) and title commensurate with experience
  • Stock options
  • Insurance coverages, including health, dental, and vision
  • 401K with company match
  • Paid time off and paid holidays
  • Close to public transportation (Amtrak, AC Transit, shuttles to BART)
  • Highly collaborative and fun work environment
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