Research Associate / Senior Research Associate – In Vivo

BreezeBio • South San Francisco, CA

6h • $80,000 - $130,000

About The Position

BreezeBio is seeking a highly motivated and technically skilled Research Associate or Senior Research Associate to join its In Vivo team. This highly practical, laboratory-based role focuses on executing in vivo studies evaluating nanoparticle-encapsulated therapeutic candidates using the company’s NanoGalaxy® hydrophilic nanoparticle platform. The position is intended for someone with substantial hands-on experience independently performing routine procedures in live mice and/or rats, and who can carry out established procedures accurately and consistently while contributing to multiple studies in a fast-paced research environment.

The position reports to the Group Lead – In Vivo and involves close collaboration with scientists and other functional teams across the organization. The role includes animal handling, dosing, blood collection, tissue and organ harvests, routine health monitoring, study execution, and accurate documentation. Candidates must have direct practical experience performing procedures on live rodents; observation, study coordination, or data analysis alone does not meet the technical requirements.

Requirements

• Bachelor’s degree in Biology, Animal Science, Biomedical Sciences, or a related field.
• At least 1 year of direct, hands-on in vivo experience with laboratory rodents for the Research Associate level, or at least 3 years for the Senior Research Associate level.
• Demonstrated practical experience performing rodent dosing procedures, particularly IV, IM, and PO administration.
• Direct experience performing rodent blood collection, particularly retro-orbital and submandibular bleeding.
• Experience performing terminal procedures and tissue or organ harvests.
• Strong animal handling skills and familiarity with routine animal care and monitoring.
• Ability to independently perform established procedures with minimal supervision and consistently generate high-quality, reproducible data.
• Strong organizational skills, attention to detail, and ability to maintain accurate laboratory records.
• Ability to work effectively in a collaborative, fast-paced, multidisciplinary environment.
• Excellent written and verbal communication skills.
• Direct, practical experience performing procedures on live rodents; observing procedures, coordinating studies, or analyzing in vivo data alone is insufficient.

Nice To Haves

• Experience with both mouse and rat models.
• Experience with pharmacokinetic (PK), pharmacodynamic (PD), and/or efficacy studies.
• Experience with fibrosis models, such as pulmonary or lung fibrosis models.
• Familiarity with rodent models of immunological disorders, autoimmune diseases, and/or genetic diseases.
• Experience with anesthesia, perfusion, and tissue processing.
• Experience working in a biotechnology or pharmaceutical research environment.
• For the Senior Research Associate level, demonstrated ability to independently execute complex in vivo procedures and studies.

Responsibilities

• Perform hands-on in vivo studies in mice and rats, including routine animal handling, dosing, blood collection, and tissue collection.
• Independently perform routes of administration, particularly intravenous (IV), intramuscular (IM), intraperitoneal (IP), and subcutaneous (SC) injections.
• Perform rodent blood collection, including retro-orbital (RO) and submandibular bleeding.
• Perform terminal procedures, including tissue and organ harvests, with appropriate sample processing and handling.
• Assist with study planning, preparation, execution, and monitoring in collaboration with team members.
• Conduct routine animal health monitoring, body weight measurements, clinical observations, and study-related assessments.
• Maintain accurate and detailed experimental records and properly document study procedures and results.
• Execute established protocols and standard operating procedures (SOPs) accurately and consistently, with attention to detail.
• Collaborate with multidisciplinary teams and communicate study progress and results effectively.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level