About The Position

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. We are seeking a Research Associate or Senior Research Associate – Cell Science to support cell line development through hands-on cell biology, CHO cell line development, and functional assay execution. This role is lab-based and requires deep experience with CHO cell culture and mammalian expression systems. You will work cross-functionally with Protein Engineering and Process Development teams to generate and characterize stable cell lines, support expression of antibody and multi-specific formats, and deliver high-quality data to advance pipeline programs. This role requires full-time onsite presence in our Redmond, WA office, with a planned relocation to our new Bothell, WA facility in fall 2026.

Requirements

  • BS or MS in Cell Biology, Molecular Biology, Biochemistry, or related field
  • Research Associate I: 1+ years of industry experience in biologics or antibody discovery
  • Senior Research Associate: 4+ years of industry experience in biologics or antibody discovery
  • Strong background in mammalian cell biology and expression systems
  • Demonstrated hands-on expertise in CHO cell culture and stable cell line development
  • Ability to thrive in a fast-paced team environment and deliver complex objectives under tight deadlines
  • CHO suspension culture and clone screening
  • Stable transfection methods
  • Cell Biology and Molecular Biology laboratory skills
  • Strong experimental design and troubleshooting skills

Nice To Haves

  • Familiarity with antibody or multi-specific biologics preferred

Responsibilities

  • Maintain mammalian cell cultures
  • Generate and maintain stable CHO cell lines for antibody expression
  • Perform transfection, clone selection, single-cell cloning, and productivity screening
  • Support cell banking activities and maintain detailed documentation
  • Perform expression vector construction, plasmid preparation, and NGS sequencing
  • Analyze and interpret experimental data
  • Maintain accurate electronic lab notebook records
  • Present findings clearly to cross-functional teams
  • Contribute to troubleshooting, assay development, and process improvements
  • Operate effectively in a fast-paced, early-stage R&D environment

Benefits

  • 100% paid employee premiums for medical/dental/vision
  • STD
  • LTD
  • a 401(k) plan with a 50% company match of up to 3%
  • a vesting schedule of only 5 years
  • 15 PTO days per year
  • sick leave
  • 11 paid holidays
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