Research Associate/Scientist I, Cell Biology

Dispatch Bio • Philadelphia, PA

7h

About The Position

Our purpose at Dispatch is to help create a world where all cancer patients can be cured. We’re humbled by the opportunity to work together as a team on some of the most pressing medical challenges of our time. To achieve our purpose, we are dedicated to engineering a universal treatment across solid tumors. We’re committed to the development of novel therapies, leveraging first-in-class technologies in viral vectors, universal targets, and novel cytokine biology. Our therapeutic approach has the potential to enable us to treat significant numbers of cancer patients and make a real and lasting impact on the world. Our company was founded on pioneering work carried out in the laboratories of Dr. Carl June (University of Pennsylvania), Dr. Kole Roybal (University of California, San Francisco), Dr. Christopher Garcia (Stanford University) and Dr. Andy Minn (Memorial Sloan Kettering Cancer Center). At our company, you would become one of our early team members— not only playing a role in meeting our ambitious mission but also building our thriving culture. We are determined to deliver with urgency to discover new solutions and we always stay dedicated to scientific rigor; we have an ownership mindset because each and every one of us is integral to our success. Collaboration is core for us because we believe that by bringing people together with diverse perspectives, we make a stronger whole. And, we show we care about our work and each other by sharing feedback - ultimately in service of our vision to empower people to continue forward with their lives – cancer free.

Requirements

• Bachelor’s or Master’s Degree in Immunology, Cell Biology, Biochemistry, or similar field
• At least one year of hands-on laboratory experience in related field
• Experience with molecular biology techniques including DNA/RNA extraction and sequencing library generation
• Proficiency in mammalian cell culture and diligent aseptic techniques
• Ability to independently execute and interpret experimental assays
• Excellent organizational, problem-solving, planning and time management skills
• Collaborative and positive attitude, ability to work in a team, and dedicated work ethic and the desire to work in a flexible and fast-paced, entrepreneurial environment
• Strong verbal and written communication skills

Nice To Haves

• Prior experience with lentivirus production
• Mouse cell/tissue harvesting and ex vivo analyses
• Proficiency in multiparameter flow cytometry and cell sorting
• Experience with T cell functional assays (e.g., cytotoxicity and cytokine assays)
• Experience with oncolytic viruses

Responsibilities

• Execute various in vitro immunoassays with CAR-T cells and/or oncolytic viruses
• Prepare genomic libraries
• Produce and titer lentivirus
• Assist with in vivo murine studies and downstream tissue processing and analysis by flow cytometry
• Maintain multiple tumor cell lines
• Document, analyze, and report experimental data in accordance with SOPs
• Effectively communicate experimental findings in team and cross-functional meetings

Benefits

• Highly competitive compensation package with meaningful ownership through equity
• Excellent coverage for medical, vision, and dental
• 401(k) with generous contribution
• Life insurance
• Flexible PTO policy
• Additional substantial benefits

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Associate degree