Research Associate RA/Sr. RA - RNA Process Development and Manufacturing

Addition Therapeutics•South San Francisco, CA

2d•$55 - $70•Onsite

About The Position

Addition Therapeutics is seeking a highly motivated scientist with experience in RNA or related modality manufacturing. This position is at the Research Associate/Senior Research Associate level. The ideal candidate will contribute to RNA production and broad operationalization of the production process. The successful candidate is detailed-oriented and who is excited by new challenges and cross-functional teamwork. This position has vast learning opportunities in the field of permanent gene insertion into the genome.

Requirements

Experience with manufacturing DNA, RNA or gene therapy related modalities (GMP or non-GMP)
Good documentation practice with experience in an electronic notebook
Thrives in a fast-moving, results-oriented startup environment
Self-motivated, passionate, and eager to continuously learn
Experience with external vendor communications.
Bachelor's or master's degree in chemistry, Biochemistry or related field with 2-4 years of experience

Nice To Haves

Experience with tangential flow filtration, AKTA purification, and bioreactors
Experience with QC assays including Qubit, Fragment Analyzer, LAL Endotoxin
Familiarity and hands-on experience in molecular biology and cell biology
Familiarity with JMP statistical software

Responsibilities

Producing RNA in small to mid-scale sized reactions
Preparing reagents, sub-aliquoting, maintaining reagent logs and inventory
Supporting reagent selection and vendor qualification
Contribute to creating and documenting protocols and techniques.
Collaborate with the analytical team to determine purity and levels of undesired impurities in DNA and RNA products.
Support QC assays
Collect and prepare accurate and timely data summaries and review written reports.
Stay current with relevant scientific literature and implement new techniques or practices to improve quality and efficiency