Research Associate, Protein Chemistry & Bioconjugation (6 MONTH CONTRACT)
About The Position
Ring Therapeutics Inc. is seeking a motivated and detail-oriented Research Associate to join our Protein Chemistry & Bioconjugation team. This is a hands-on bench role focused on supporting the production, modification, and characterization of antibodies, proteins, and bioconjugates that underpin our targeted therapeutic programs. The ideal candidate has a solid foundation in standard protein workflows and bioconjugation chemistry and can generate high-quality, decision-driving data to advance platform development. Experience with or exposure to ADC or other biologics research and development is particularly desirable. This is a highly collaborative, hands-on role requiring scientific independence and a strong focus on delivering well-characterized, high-quality protein and conjugate inputs to enable downstream assay development and candidate selection.
Requirements
- S. or M.S. in Biochemistry, Bioengineering, Chemistry, or a related field
- 1–3+ years of hands-on laboratory experience in a biotech, pharma, or academic research setting
- Demonstrated proficiency in standard protein workflows: Protein concentration measurement (UV-Vis spectroscopy, BCA, Bradford)
- Protein characterization techniques (SDS-PAGE, DLS)
- Buffer preparation and formulation
- Buffer exchange via dialysis
- Hands-on experience with at least one bioconjugation chemistry approach (e.g., NHS ester, maleimide, click chemistry)
- Strong attention to detail, excellent organizational skills, and rigorous documentation habits
- Ability to work independently and collaboratively in a fast-paced research environment
Nice To Haves
- Experience with antibody-drug conjugates (ADCs)
- Familiarity with TFF systems including µPulse TFF
- Experience with SEC-HPLC or analytical HPLC for purity/conjugation analysis
- Experience with protein purification workflows including IMAC, SEC, and ion exchange chromatography
- Experience with data analysis tools (GraphPad Prism, imageJ)
Responsibilities
- Execute common bioconjugation reactions.
- Prepare and characterize antibody- and protein-conjugated constructs (e.g., fluorophore labeling and payload attachment).
- Perform post-conjugation purification techniques including desalting columns and TFF.
- Perform standard protein analytics and concentration measurements
- Prepare formulation buffers and working reagents
- Conduct buffer exchange and protein concentration
- Maintain accurate experimental records and SOPs in an electronic lab notebook (ELN)
- Ensure proper inventory management of reagents, consumables, and protein stocks
- Present data clearly and provide actionable recommendations to project teams
- Collaborate cross-functionally with targeting, protein engineering, analytical, and translational teams to ensure materials align with program needs
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
