About The Position

Sygnature Discovery is currently looking for a candidate for the position of Research Associate at its research center. The company provides a variety of preclinical services to the pharmaceutical and biotechnology industry helping them in their drug discovery and development.

Requirements

  • MSc in Organic Chemistry or Medicinal Chemistry
  • Strong knowledge and experience in current synthetic methods
  • Expertise in isolation and purification techniques such as silica gel chromatography and HPLC as well as modern analytical techniques such as NMR and LCMS
  • Knowledge of good laboratory and safety practices
  • Excellent written, organizational and documentation skills
  • Proactive with strong interpersonal skills; able to thrive in a team-based environment
  • Demonstrated ability to troubleshoot and creatively problem solve
  • Proficiency in Microsoft Office (Word, Excel and PowerPoint)
  • Ability to communicate progress effectively with colleagues and managers
  • Applicants must be eligible to work in Canada (Canadian citizen, permanent resident or work permit)

Responsibilities

  • Utilize cutting-edge synthetic methodologies and techniques to design and execute efficient syntheses of target compounds for existing chemical series and novel series
  • Independently conduct multi-step synthesis and optimization through effective reaction planning, troubleshooting, and systematic analysis
  • Purify and characterize compounds using a variety of techniques including column chromatography, crystallization, trituration, LCMS, NMR, HPLC
  • Work under the supervision of the Director of Chemistry or the Project Manager in order to achieve the objectives of the project in line with those of the client
  • Research current literature to formulate synthetic and medicinal chemistry strategies. Evaluate and implement new reactions, techniques and technologies to advance the projects
  • Maintain lab notebook, instrument and inventory records in accord with department guidance
  • Maintain all appropriate standards for lab safety and hazardous material management

Benefits

  • Full-time permanent position
  • Health and dental care insurance plan
  • Short- and long-term disability insuranc
  • Life insurance
  • 3 weeks vacations
  • RRSP employer’s matching program
  • Telehealth program
  • Casual dress code
  • Flexible schedule
  • Personal days
  • On-site free parking
  • Continuing training
  • Career development
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