Research Associate II, Konermann Lab

Arc Institute • Palo Alto, CA

4h • Onsite

About The Position

This is a Research Associate II position in the Konermann Lab at Arc Institute and the Stanford Medical School Department of Biochemistry, working closely with a scientist in the lab to identify the key pathways that drive the progression of neurodegenerative diseases using advanced CRISPR technologies and functional assays. The position offers an opportunity to learn various cutting-edge techniques while participating in a project at the intersection of neuroscience, stem cell biology, and genomics. It also provides experience in experimental planning, execution, analysis, troubleshooting, and data interpretation with a high degree of independence. This role is suitable for candidates considering a PhD program, as they will be involved in all stages of a project under the guidance of an experienced scientist. Additionally, the role offers broad experience in collaboration with a cross-functional team to develop expertise in biomedical research for a career in the R&D sector of the industry.

Requirements

• BS/MS or equivalent professional experience in cellular biology, neuroscience, immunology, or another relevant field.
• 2+ years of relevant experience (including independent lab work during your undergraduate studies) incorporating strong hands-on experience with cell culture techniques and cell-based assays.
• Strong critical thinking and problem-solving skills.
• Strong oral and written communication skills.
• You’re both a strong individual contributor as well as a collaborative team member.
• Eager to collaborate with a cross-functional team at Arc spanning the Konermann lab, the Multi-Omics Tech Center, and the Cellular Model Team.

Nice To Haves

• Experience working with human ESC/iPSCs and neural and/or immune cell types is a plus for this position.
• Experience with computational analysis for multiomics is a plus for this position.
• Experience with molecular biology such as protein purification and immunoprecipitation is a plus for this position.

Responsibilities

• Perform molecular and cellular experiments including mammalian cell culture, transfection, Western blot, RT-qPCR, and immunostaining.
• Perform imaging-based screening at the organelle level (particularly, lysosome and lipid droplet).
• Perform lipid-based assay including lipid extraction and lipidomics.
• Collaborate closely with a scientist in the laboratory to conduct large-scale screening of genetic modifiers of neurological diseases such as Alzheimer’s disease using stem cell-derived brain models.
• Learn various cutting-edge techniques while participating in a project at the intersection of neuroscience, stem cell biology, and genomics.
• Learn to conduct experimental planning, execution, analysis, troubleshooting, and data interpretation with a high degree of independence and continued support from the rest of the team.
• Collaborate with a cross-functional team to develop expertise in biomedical research.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Associate degree