Research Associate II/ Senior Research Associate I

Arcturus Therapeutics Inc•San Diego, CA

4d•$80,000 - $105,000

About The Position

The Research Associate II / Senior Research Associate will support the Analytical Development team by performing analytical testing, method development, and characterization of RNA-based drug substances, intermediates, and formulated drug products. This position supports multiple development programs, including early research through clinical development, by generating high-quality analytical data to enable process development, formulation development, stability studies, and product characterization. The successful candidate will work in a collaborative, fast-paced environment and contribute to the development, optimization, qualification, and execution of analytical methods for nucleic acid therapeutics.

Requirements

Bachelor’s degree in Chemistry, Biochemistry, Molecular Biology, Pharmaceutical Sciences, or related scientific discipline.
Research Associate II: BS with 2+ years of relevant industry experience.
Senior Research Associate: BS with 5+ years of relevant industry experience or MS with 2+ years of industry experience.
Experience analyzing scientific data and troubleshooting laboratory experiments.
Ability to manage multiple priorities while maintaining data quality.
Strong attention to detail and organizational skills.
Ability to independently execute routine laboratory work while recognizing when guidance is needed.
Proficiency with Microsoft Office and scientific software
Strong written and verbal communication skills.
Excellent organizational and time management abilities.
Ability to work independently and collaboratively in a multidisciplinary environment.
Demonstrated scientific curiosity and willingness to learn new analytical techniques.
Strong problem-solving skills and attention to detail.
High level of integrity and commitment to data quality.

Nice To Haves

Experience supporting analytical development for biologics or nucleic acid therapeutics.
Experience with HPLC/UPLC, CE, Fragment Analysis, UV-Vis spectroscopy, fluorescence assays, or related analytical techniques.
Familiarity with analytical method development and qualification.
Experience with electronic laboratory notebooks (ELN).
Experience supporting stability studies and analytical characterization.
Knowledge of GMP/GDP documentation practices is a plus.

Responsibilities

Perform analytical testing of RNA drug substances, intermediates, and formulated drug products using a variety of analytical techniques.
Execute analytical methods including chromatography, electrophoresis, spectroscopy, fluorescence-based assays, particle characterization, and other physicochemical characterization techniques.
Support development, optimization, troubleshooting, qualification, and transfer of analytical methods.
Analyze, interpret, and summarize experimental data and communicate results to project teams.
Maintain accurate laboratory documentation, electronic laboratory notebooks (ELNs), and technical reports in accordance with company documentation practices and ALCOA principles.
Support laboratory equipment qualification, calibration, routine maintenance, and troubleshooting.
Manage analytical reagents, reference standards, laboratory inventory, and sample tracking.
Collaborate effectively with cross-functional teams, including Process Development, Formulation Development, Quality Control, and Manufacturing.
Present scientific findings during team meetings.
Perform additional responsibilities as assigned.