Research Associate II, Delivery

AskBioDurham, NC
Onsite

About The Position

AskBio Inc., a subsidiary of Bayer AG, is a gene therapy company focused on developing life-saving medicines. The company has a portfolio of clinical programs for various diseases and utilizes proprietary technologies like Pro10™ for manufacturing. With global headquarters in Research Triangle Park, North Carolina, and European headquarters in Edinburgh, Scotland, AskBio is dedicated to pioneering science and creating transformative molecular medicines. The Research Associate II will support AAV delivery research within the Delivery organization in R&D, providing hands-on experimental support for molecular biology and cell-based workflows to advance the company's preclinical gene therapy pipeline. This role involves working closely with scientists to execute protocols, generate data, and support laboratory operations. The position is based in Morrisville, North Carolina.

Requirements

  • Bachelor's degree in Molecular Biology, Biochemistry, Biotechnology, or a related scientific field with 2+ years of relevant laboratory experience; OR a Master’s degree in Molecular Biology, Biochemistry, Biotechnology, or a related scientific field
  • Hands-on experience with molecular biology techniques, including DNA/RNA isolation, SDS-PAGE, qPCR, ddPCR and Western blot
  • Prior experience with mammalian cell culture and aseptic technique
  • Strong technical laboratory skills with the ability to independently execute protocols and experiments
  • Ability to follow established protocols with minimal supervision and deliver reliable, reproducible results
  • Strong organizational skills, attention to detail, and commitment to accurate documentation
  • Ability to manage multiple tasks simultaneously and work effectively within a collaborative, cross‑functional team environment
  • Proficiency with basic data analysis and common laboratory software tools (e.g., Excel, GraphPad)

Nice To Haves

  • Experience supporting AAV research or delivery programs, including familiarity with viral vectors or gene therapy concepts
  • Exposure to AAV production or purification workflows at a research scale
  • Experience preparing samples for downstream analyses such as NGS or other advanced molecular assays
  • Comfort working across diverse experimental workflows and learning new techniques as project needs evolve

Responsibilities

  • Perform plasmid purification, genomic DNA extraction, RNA extraction, and PCR-based assays (PCR, qPCR, ddPCR)
  • Conduct routine mammalian cell culture activities, including maintenance of adherent cell lines and execution of cell-based assays following established SOPs
  • Perform in vitro assays including transfection and AAV transduction
  • Support in vitro and in vivo studies through sample preparation, tissue processing, and downstream molecular analyses
  • Accurately document experimental procedures and results in an electronic laboratory notebook in accordance with data integrity standards
  • Analyze data, summarize results, and communicate findings through internal reports or presentations
  • Maintain laboratory organization, including reagent preparation, inventory management, and inspection readiness
  • Contribute to continuous improvement of laboratory workflows by following SOPs and escalating issues appropriately

Benefits

  • AskBio Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race, color, religion, gender, sexual orientation, gender identity, national origin, age, disability, veteran status or any other protected status prohibited under Federal, State or local laws. All employment decisions are based on valid job‐related requirements.
  • If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening by calling us at (919) 561-6210 or sending us an email at [email protected].
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