Research Associate I- Alexanian Lab

Gladstone Companies•San Francisco, CA

2d•Onsite

About The Position

The Alexanian Lab at the Gladstone Institutes is seeking a curious and motivated Research Associate (RA) to join their growing team. This new lab is dedicated to understanding the gene-regulatory and epigenetic mechanisms that govern cellular plasticity in both normal and disease contexts, with a particular focus on heart disease. The long-term goal is to uncover insights that can inform new therapies targeting gene regulation in chronic diseases characterized by harmful changes in cell behavior and tissue structure.

Requirements

BA/BS degree in a related field.
Excellent teamwork, organizational, communication, and time-management skills.
Highly self-motivated, reliable, and responsible.
Excellent organizational and interpersonal communication skills (verbal and written).
Willingness and ability to learn new skills and explore.
Ability to work independently and as a member of a research team.
Excellent organization and time management skills.
Attention to detail in experimental techniques and record keeping.
1+ years of wet lab experience (in addition to lab coursework).

Responsibilities

Perform molecular biology techniques including cloning, plasmid DNA preparation, PCR, gel electrophoresis, RNA isolation, qRT-PCR, and chromatin immunoprecipitation.
Conduct cell culture experiments with primary cells and human stem cells, including transfection and virus production.
Gain hands-on experience with genomic technologies such as single-cell RNA-seq, ATAC-seq, CRISPR-based screening, CUT&RUN, and PRO-seq.
Support the analysis of large-scale genomic datasets, contribute to data processing and visualization, and participate in projects using machine learning models.
Manage mouse colonies, perform genotyping, dissections, and breeding design.
Assist in maintaining lab operations through ordering, supply management, and equipment upkeep.