Research Associate I, Biochemistry & Molecular Biology (Galveston)

University of Texas Medical Branch (UTMB)Galveston, TX
Onsite

About The Position

The Center for Genome Architecture studies how the genome folds inside the nucleus and what that folding does. Work from the Center produced the first kilobase-resolution three-dimensional maps of the human genome, identified chromatin loops and contact domains as fundamental features of genome organization, showed that loop extrusion explains how these structures form, demonstrated that acute loss of cohesin eliminates loop domains genome-wide, and discovered fossil chromosomes in ancient DNA. We are expanding our experimental footprint, including a growing program of mouse work, to ask how these principles operate in living tissues. This position performs molecular biology and sequencing library preparation and analysis, maintains careful records across a large experimental series, contributes to quality control of the resulting data, and takes part in supervised mouse work including colony management, genotyping, treatment, and tissue collection. Training is provided.

Requirements

  • Bachelor's degree in basic science or equivalent
  • Biological Analysis
  • Quantitative Analysis
  • Qualitative Analysis
  • Tabulation of Data
  • Equipment Calibration
  • Standard Laboratory

Nice To Haves

  • Undergraduate research experience is valued
  • Prior mouse experience is a plus

Responsibilities

  • Performs varying standardized laboratory assignments and experiments.
  • Under direct supervision, performs standard research assignments involving a series of related operations.
  • Sets up and conducts standard research experiments following detailed technical instructions.
  • Prepares biological assays and conducts basic quantitative and qualitative analysis.
  • Maintains records of all tests performed and data collected.
  • Assists in the compilation and tabulation of data and provides preliminary analysis.
  • Assembles, calibrates, operates and makes minor modifications to a variety of laboratory equipment as defined by appropriate guidelines.
  • Adheres to internal controls established for department.
  • Performs molecular biology and sequencing library preparation and analysis.
  • Maintains careful records across a large experimental series.
  • Contributes to quality control of the resulting data.
  • Takes part in supervised mouse work including colony management, genotyping, treatment, and tissue collection.
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