Research Associate I/II, In Vivo Immunology

Azalea Therapeutics•Berkeley, CA

5d•Onsite

About The Position

Azalea Therapeutics is enabling precision genome engineering directly inside the body, with an initial focus on creating cancer immunotherapies in vivo. Azalea is pioneering a new way to turn a person’s own T cells into a powerful cancer therapy — directly inside the body. Instead of removing cells and manipulating them in a lab, we use precision genome editing tools to engineer T cells where they already live. At the center of our approach are Enveloped Delivery Vehicles, or EDVs. As highly selective couriers, EDVs are designed to specifically locate T cells within the patient and deliver our genome engineering cargo. Once inside the cell, the anti-cancer agent is inserted into a precise site in the genome, ensuring safe and potent modifications to fortify the T cells against cancers. Why this matters: We aim to make cell therapy faster and more accessible by avoiding complex manufacturing outside the body. Our platform is designed for precision, so the right cells are safely programmed to effectively fight cancer. This technology has the potential to treat a wide range of cancers with a streamlined, scalable process. Our goal is simple: develop next-generation delivery technologies to bring genetic engineering and cell therapies to more patients.

Requirements

BS/BA in Molecular or Cell Biology or related life sciences discipline.
1+ years of hands-on laboratory research experience in an academia or industry setting; experience supporting in vivo pharmacology studies is preferred.
Experience handling rodents and/or assisting with in vivo studies, including dosing, sample collection, or tissue processing.
Familiarity with aseptic technique, mammalian cell culture, and standard laboratory practices.
Strong organization skills with the ability to maintain accurate experimental records using electronic notebooks (ELNs).
Ability to rapidly learn new technical skills as well as teach others.
Ability to work both collaboratively and individually in a fast-paced research environment.
Excellent communication, organizational and interpersonal skills with a strong attention to detail.

Nice To Haves

1-3 years of laboratory research experience, in academia or industry, supporting in vivo pharmacology, immunology, oncology or related research programs.
Hands-on experience with rodent handling, restraint, and dosing via IV, IP, SC, and/or PO routes.
Experience collecting and processing blood and tissue samples for downstream molecular or cellular analyses.
Experience maintaining mammalian cell cultures and preparing cells for in vivo studies.

Responsibilities

Perform and support in vivo pharmacology studies in rodent models, including dosing (IV, IP, SC, PO) and tissue collection.
Collect and process biological samples (blood, spleen, liver, and other organs) for downstream analysis.
Assist in the development and optimization of in vivo disease models.
Maintain and propagate ex vivo cell lines for in vivo studies.
Manage the inventory of in vivo supplies across all laboratories.
Maintain detailed and organized notes and results within an electronic notebook.
Ensure compliance with IACUC protocols and maintain high standards of animal welfare.
Analyze data and communicate results within a team setting.
Work closely with the supervisor to schedule and prioritize workload to manage several tasks simultaneously.
Additional duties and responsibilities as required based on the needs of the company.