Research Associate I/II I-O
About The Position
SystImmune Inc. is seeking a motivated Research Associate I/II to join the Bioassay team within the Immuno-Oncology department. This role will support the engineering of complex cell lines and the execution of cell-based immunoassays to enable the discovery and development of novel cancer therapeutics. The ideal candidate will be a strong experimentalist with direct experience in genetic modification (such as lentiviral transduction and knock-in/out) and bioassay execution who thrives in a fast-paced, collaborative environment. This is a hands-on laboratory role focused on critical materials generation, assay execution, and data analysis. The successful candidate will maintain high-quality experimental standards while developing deep technical expertise in immuno-oncology drug development. This role is full-time onsite in Redmond, WA and will move to Bothell, WA fall 2026.
Requirements
- BS or MS in Biology, Immunology, Cell Biology, Bioengineering, Biochemistry, or related scientific field
- Minimum 1+ year of industry laboratory experience (internships may be considered if highly relevant) for Research Associate I
- Hands-on experience with mammalian cell culture techniques and aseptic techniques
- Experience with mammalian cell culture techniques
- Exposure to genetic modification workflows such as transient transfections or lentiviral transduction
- Basic familiarity executing immunoassays such as ELISA or flow cytometry
- Strong organizational skills and attention to detail
- Ability to work effectively in a team environment
- BS or MS in a relevant scientific discipline for Research Associate II
- Typically, 2–4 years of relevant industry experience for Research Associate II
- Direct experience engineering cell lines, including executing lentiviral transductions and knock-ins for Research Associate II
- Proven track record executing and troubleshooting cell-based assays and flow cytometry workflows for Research Associate II
- Demonstrated ability to work with moderate independence for Research Associate II
Nice To Haves
- Experience supporting oncology, immuno-oncology, immunology, or biologics drug discovery programs.
- Experience with single-cell cloning, CRISPR/Cas9 workflows, or stable cell line selection.
- Proficiency with Incucyte live-cell imaging, multi-color flow cytometry, or MSD multiplex platforms.
- Exposure to high-throughput research settings or regulated laboratory environments.
- Strong data analysis software skills (e.g., GraphPad Prism, FlowJo) and scientific communication skills
Responsibilities
- Engineer stable cell lines using lentiviral transduction, CRISPR knock-ins, and knock-outs
- Analyze complex datasets, prepare technical reports, and present findings to internal teams.
- Perform rigorous batch qualification of critical reagents and cell lines to ensure assay consistency.
- Maintain and manipulate complex co-cultures of primary immune cells and engineered cancer cell lines.
- Conduct functional assays using Incucyte live-cell imaging, flow cytometry, and ELISA-based platforms.
- Develop, optimize, and validate cell-based and immunoassays to support drug development programs.
Benefits
- 100% paid employee premiums for medical/dental/vision
- STD, LTD
- 401(k) plan with a 50% company match of up to 3%
- 15 PTO days per year
- Sick leave
- 11 paid holidays
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Education Level
Associate degree
