Research Associate-Hematology

The Ohio State University • Columbus, OH

3d • Onsite

About The Position

We are seeking a highly motivated Researcher 1 to support research at the intersection of hematology, immunology, and cancer biology. This position is well suited for individuals with strong wet lab expertise who are eager to apply multi-omic approaches to biologically and clinically meaningful questions, with an appreciation for complementary quantitative or computational methods. The successful candidate will contribute to studies of hematopoietic differentiation, leukemia–immune interactions, and the development of immune-based therapeutic strategies, including CAR-T cell approaches.

Requirements

• Bachelor’s degree in Biology, Immunology, Molecular Biology, or a related field.
• Research laboratory experience with hematopoietic, leukemia, or immune-based assays and standard molecular/cellular techniques.
• Experience working with human or murine blood and bone marrow samples in BSL-2 settings.
• Strong analytical skills, attention to detail, and ability to work collaboratively.
• Commitment to scientific rigor, integrity, and reproducibility.
• Successful completion of a background check.

Nice To Haves

• Master’s degree in a related field or equivalent research experience.
• Experience with bone marrow–derived cells, hematopoietic stem/progenitor assays, or leukemia models.
• Proficiency in high-dimensional flow cytometry, including panel design and analysis.
• Experience with T cell assays, viral transduction, CAR-T approaches, or gene editing.
• Familiarity with murine models of leukemia or immune response.
• Strong organizational skills and adaptability in a fast-paced research environment.
• Detail-oriented, with careful adherence to protocols.
• Strong willingness to learn new techniques and adapt to unfamiliar workflows.
• Reliable, organized, and able to work both independently and collaboratively.
• Positive responsiveness to feedback.
• Positive attitude, scientific curiosity, and motivation to grow in a translational research environment.

Responsibilities

• Design, plan, and execute research projects focused on hematopoiesis, leukemia, and tumor immunology.
• Perform molecular and cellular biology techniques, including DNA/RNA extraction, RT-PCR, cloning, bacterial transformation, plasmid isolation, transfection, viral transduction, and CRISPR-Cas9 gene editing.
• Conduct bone marrow and blood-based assays, including collection, processing, enrichment, and analysis of hematopoietic, leukemic, and immune cell populations.
• Perform high-dimensional flow cytometry (panel design, staining, acquisition, and analysis) and support T cell functional assays, including CAR-T cell generation and immune effector testing.
• Carry out immunohistochemistry, Western blotting, tissue culture, and related assays to support mechanistic studies.
• Analyze and integrate multi-omic datasets (including bulk and single-cell sequencing, epigenomic, and spatial data).
• Curate and analyze public datasets and clinical cohorts.
• Perform statistical analysis, data visualization, and figure generation for manuscripts and presentations.
• Collaborate closely with experimental researchers to interpret results and inform experimental design, and develop reproducible, well-documented analysis workflows.
• Participate in murine models of leukemia and cancer, including injections, monitoring, and collection of bone marrow and tissues for downstream analyses.
• Interpret experimental data, review relevant scientific literature, and contribute to manuscripts, figures, grant applications, and presentations for scientific meetings.
• Maintain accurate experimental records and data organization.
• Support laboratory operations, including inventory management, ordering, and equipment maintenance.
• Train and assist research staff, participate in lab meetings, and contribute to troubleshooting and protocol optimization.

Benefits

• Medical, dental and vision coverage, with Ohio State paying a significant portion of the cost.
• Paid time off, including sick and vacation time and 11 holidays.
• State retirement plan or an alternative retirement plan, both with generous employer contributions.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level