Research Associate, Formulation Development

Pivotal • San Diego, CA

3d • $65,000 - $100,000 • Onsite

About The Position

We are seeking a highly motivated and skilled individual to join our team as a Research Associate in Formulation Development. The successful candidate will be responsible for designing, executing, analyzing, and making recommendations on research protocols for lipid nanoparticle (LNP) drug delivery systems aimed at gene editing. Title level and salary will be commensurate with experience.

Requirements

• Bachelor's degree or higher in Chemistry, Pharmaceutics, Biochemistry, Biomedical Engineering, Chemical Engineering, or a related field.
• 3+ years of experience in pharmaceutical formulation, with a focus on lipid nanoparticle drug delivery systems.
• Experience with techniques such as DLS, zeta potential measurement, and other analytical tools used in nanoparticle characterization.
• Strong analytical and problem-solving skills.
• Excellent communication and teamwork abilities.
• Ability to work independently and manage multiple tasks effectively.
• Eligible to work in the United States for any employer without current or future sponsorship.
• Able to work onsite in the lab, based on the location listed for the position (either San Diego, CA or Boston, MA).
• Direct candidates only and not from a third party, i.e., staffing agency.

Nice To Haves

• GMP production experience.
• Familiarity with regulatory requirements and quality control in bioprocessing.

Responsibilities

• Develop lipid nanoparticle (LNP) formulations for gene editing applications.
• Conduct experiments to optimize formulation parameters such as particle size, encapsulation efficiency, and stability.
• Optimize production processes to improve yields and scalability.
• Troubleshoot and resolve issues related to formulation processes.
• Perform analytical characterization of LNPs using techniques such as dynamic light scattering (DLS), zeta potential measurement, and electron microscopy.
• Support in vitro and in vivo studies to evaluate the efficacy and safety of LNP formulations.
• Collaborate with preclinical and clinical teams to ensure successful translation of formulations.
• Maintain accurate and detailed laboratory records.
• Prepare technical reports and presentations to communicate findings.
• Stay current with advancements in LNP technologies and methodologies.

Benefits

• Competitive salary, equity, and benefits package.
• Opportunities for professional growth and development.
• Fast paced collaborative and innovative work environment.
• Medical, Dental, Vision, Life, Disability, a 401k Match of 4%, Paid Time Off and Equity.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level