Antibody Characterization Research Associate

Institute for Protein InnovationBoston, MA
$65,000 - $75,000Onsite

About The Position

The Institute for Protein Innovation (IPI) is a nonprofit research organization dedicated to advancing protein science to accelerate research and improve human health. Founded in 2017 and located in Boston’s Longwood Medical Area, IPI focuses on building protein tools, conducting internal research, and developing educational programs. With a significant endowment, IPI offers a unique environment that blends academic freedom with industrial-scale efficiency to tackle transformative projects. The Institute has established a robust platform for discovering, developing, and distributing synthetic antibodies and other protein tools for the biomedical community. IPI's expertise, collaborative culture, and research tools are driving new biomedical and therapeutic discoveries, fostering a growing network of researchers from institutions like Harvard Medical School and Boston Children's Hospital.

Requirements

  • B.S. or M.S. in biology, molecular biology, biochemistry, or related field with 0-2 years’ experience in biotechnology, pharmaceutical, or academic settings.
  • Basic molecular biology and biology lab skills required.
  • Hands-on experience with cell culture required.
  • Strong problem-solving, critical-thinking, and communication skills.
  • Detail-oriented with the ability to follow SOPs and execute bench experiments successfully.
  • Exceptional organizational and time-management skills.
  • Team-oriented spirit with a strong commitment to impactful science.

Nice To Haves

  • Experience with automated lab systems, basic molecular genetics techniques, CHO transfection systems, and immunohistochemistry preferred.
  • Programming skills (R, Python) for data analysis and visualization are a plus.

Responsibilities

  • Perform transient transfection and immunofluorescence of CHO cells with antibody targets and closest related proteins to test activity and selectivity of IPI antibodies.
  • Perform immunohistochemistry testing of specific, sensitive antibodies on mouse tissue.
  • Assist in method development and optimization for immunofluorescence assays.
  • Culture, transfect, and maintain mammalian cells.
  • Perform immunofluorescence, immunocytochemistry, and knockout/knockdown assays to test IPI antibodies in mammalian cells.
  • Troubleshoot technical issues and optimize processes.
  • Support automation efforts to improve throughput and consistency of immunofluorescence experiments.
  • Maintain stocks of common lab reagents for immunofluorescence and immunohistochemistry assays, including mouse tissue cryosections.
  • Document experimental protocols, raw data, and reports in an electronic laboratory notebook.
  • Present experimental results clearly and effectively.
  • Collaborate across diverse interdisciplinary teams.

Benefits

  • 100% employer-paid medical, dental, and vision plans
  • Flexible spending accounts and a healthcare reimbursement account
  • 401(k) plan with generous 6% employer match – immediately 100% vested
  • Generous PTO package
  • Commuter and parking reimbursement
  • Career development opportunities
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