Research Assistant | Laboratory of Systems Cancer Biology

Rockefeller UniversityNew York, NY
Onsite

About The Position

The Tavazoie Lab at The Rockefeller University is seeking a motivated and detail-oriented Research Assistant to contribute to their research on the fundamental principles of cancer metastasis, genomics, and gene regulation in cancer. The role involves training in a variety of in vitro, in vivo, and in silico experimental techniques to support collaborative research projects. The successful candidate will be instrumental in experimental execution, data generation, and quality control, working closely with a senior scientist. The lab focuses on understanding the molecular and cellular mechanisms of cancer metastasis, which is the primary cause of cancer-related deaths. They employ a multidisciplinary approach, including molecular, biochemical, computational, imaging, and clinical association methods, to study the critical regulatory pathways involved in metastasis. By implanting human cancer cells into mice, they investigate and intervene in the metastatic process. Their research has identified microRNAs that suppress metastasis, and future work aims to elucidate the mechanisms by which these molecules inhibit metastasis, with the goal of improving therapeutic strategies against it.

Requirements

  • BS or MS degree in Biology, Biochemistry, or related field
  • Strong organizational skills and attention to detail
  • Ability to work both independently and collaboratively in a fast-paced research setting
  • Clear communication skills and a high level of scientific integrity
  • Team-oriented with excellent written and verbal communication skills, collaboration skills and an eagerness to learn
  • Basic experience with standard and/or advanced data analysis software tools (Excel, R, or similar)

Nice To Haves

  • Prior laboratory experience and demonstrated familiarity with basic molecular biology techniques
  • Experience with RNA isolation and tissue culture
  • Familiarity with handling research animals (mice)

Responsibilities

  • Maintain cell cultures and perform cell based in vitro assays
  • Perform molecular assays including but not limited to protein and RNA analysis, qPCR, W-blots, ELISA and library preparation
  • Maintain mice colonies including genotyping and breeding
  • Perform tumor growth studies in mouse models, administration of test articles, sample collection and tissue processing
  • Learn and assist in analyzing sequencing data using established pipelines
  • Maintain detailed experimental records of laboratory procedures and results
  • Assist and collaborate with internal and external researchers in interpretation of the data
  • Support general lab operations, including reagent management, ordering and the generation and maintenance of lab inventories
  • Participate actively in lab meetings and scientific discussions

Benefits

  • On-the-job training and supervision
  • Opportunity to gain experience for PhD or MD-PhD programs
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