Research Assistant – GZhou Lab

The Wistar Institute•Philadelphia, PA

22h•Onsite

About The Position

The Wistar Institute has an opening for a highly motivated Research Assistant to work in the laboratory of Dr. Guangfeng Zhou as part of the Center for Advanced Therapeutics (CAT) at The Wistar Institute. The GZhou lab develops physics-based and AI-based computational methods to accelerate therapeutic discovery. His current program focuses on developing AI-based and physics-based computational approaches for drug discovery, including models that integrate physical and chemical principles, docking and binding-affinity prediction methods, and AI-accelerated virtual-screening platforms to identify and prioritize promising therapeutic leads. The successful candidate will contribute to AI-accelerated virtual screening and computational drug discovery projects in the lab.

Requirements

A bachelor’s degree in a science-related field, or equivalent combination of education and experience, is required.
Excellent communication and organizational skills are essential.

Nice To Haves

Previous experience in computational chemistry, structural biology, bioinformatics, molecular modeling, or programming is desirable but not required.
Experience with Python, Linux, high-performance computing (HPC) environments, molecular visualization, or data analysis would be advantageous.
Strong motivation to learn, attention to detail, and enthusiasm for working in a collaborative and interdisciplinary research environment.

Responsibilities

Prepare and curate protein and small-molecule datasets.
Perform molecular modeling and AI-accelerated virtual screening.
Analyze computational results and prioritize compounds for experimental testing.
Collaborate with computational and experimental researchers.
Support the development and application of computational drug-discovery workflows.