Research Assistant

GT Bio • Cambridge, MA

3d • Onsite

About The Position

GT Biosciences is seeking a highly motivated and dependable Research Associate to join our Platform Development Team and support lipid nanoparticle formulation and RNA delivery. This is a hands-on laboratory role designed for someone eager to learn, take some ownership, and grow within a fast-moving, science-obsessed startup environment. From day one, you will work directly alongside scientists with world-leading expertise in RNA delivery, LNP engineering, in vivo screening, and translational biotechnology. Our commitment is to teach you new methods and help you build a broad wet-lab skill set. Your job is to learn quickly, execute carefully, and keep going when experiments are difficult. We’re looking for someone eager to learn and improve in a fast-paced environment. This is an in-person position based in Cambridge, MA.

Requirements

• B.S. or M.S. in Chemistry, Biochemistry, Bioengineering, Biology, Pharmaceutical Sciences, or a related field.
• At least 1+ years of meaningful hands-on experience in a wet laboratory setting (academic or industry).
• Demonstrated reliability, attention to detail, and strong commitment to accurate, thorough record-keeping.
• Proficiency with basic laboratory techniques (e.g., buffer preparation, serial dilution, accurate pipetting, and nucleic acid handling).
• A fast learner who is excited to develop unfamiliar wet-lab skills and become progressively more independent.
• Persistence when experiments fail, with the ability to stay calm, investigate possible causes, and improve the next attempt.
• A proactive, team-first attitude with strong ownership, clear communication, and consistent follow-through.
• Ability to work onsite five days per week at our Cambridge, MA location.

Nice To Haves

• Basic coding or data analysis skills (e.g., Python, R, or Excel for data organization).
• Familiarity with automated liquid handling or high-throughput screening platforms.
• Experience preparing formulations or samples for animal studies.
• Mouse intravenous injection, perfusion, or tissue collection experience.
• Strong interest in RNA medicines, drug delivery, and central nervous system therapeutics.

Responsibilities

• Prepare and formulate lipid nanoparticles and related non-viral delivery systems for mRNA and siRNA using established and evolving protocols.
• Support formulation screens by varying lipid composition, component ratios, buffers, mixing conditions, and other process parameters.
• Perform formulation characterization and quality control measurements (e.g., particle size, PDI, encapsulation efficiency, RNA concentration, pH, and fluorescence-based assays).
• Prepare high-quality formulations and samples for in vitro and in vivo studies, including dose calculations, labeling, quality control, and sample tracking.
• Maintain basic cell culture responsibilities and support transfection, expression, and knockdown assays as required.
• Handle precision liquid-handling tasks with accuracy and care (e.g., multichannel pipetting, reagent pooling, serial dilutions).
• Keep meticulous laboratory records and documentation, troubleshoot experiments thoughtfully, and repeat work carefully when results do not meet expectations.

Benefits

• Flexible, generous health benefits upon conversion to full-time employment.
• Work with a small, world-leading team that values rigorous science and candid collaboration.
• Learn directly from experts.
• Rapid professional growth through hands-on training and meaningful scientific ownership.

What This Job Offers

• Career Level: Entry Level
• Education Level: Associate degree