RESEARCH ASSISTANT I - Dik Lab

Scripps Research • San Diego, CA

4d • $21 - $25 • Onsite

About The Position

The successful candidate will join the early-stage discovery research team at Calibr-Skaggs Institute for Innovative Medicines and contribute to both drug discovery and protein engineering programs. A major responsibility will be validating potential drug candidates ("hit compounds") that emerge from DNA-Encoded Library (DEL) screening campaigns across multiple therapeutic areas.

Requirements

• Requires a Bachelor’s degree in a relevant scientific discipline or an equivalent combination of education, training and/or experience from which comparable knowledge, skill and abilities have been attained.
• Requires 1-3 years experience. Candidates possessing a Master’s degree, 0-2 years experience required.
• Bachelor’s Degree in biochemistry, molecular biology, cell biology or related area.
• Highly motivated, creative, and devoted to project goals.
• Able to collaborate proficiently and communicate effectively with colleagues.
• Able to contribute in a meaningful way to scientific discourse.

Nice To Haves

• Skills in molecular biology including DNA isolation and purification, plasmid design, and cloning are required.
• Experience in mammalian cell culture, protein expression platforms (i.e. HEK, CHO, or coli), and an understanding of protein purification techniques is preferred.
• Additional experience in HPLC and/or LC-MS is advantageous, but not required.
• Willingness to learn and perform animal work at a later stage for therapeutic evaluation.
• Experience using graphing programs such as Prism and Excel is important.
• Outstanding organizational skills and experience in preparing and presenting scientific data is important.

Responsibilities

• Validate and characterize hit compounds identified through DEL screening.
• Develop, optimize, and perform biochemical and biophysical assays.
• Produce and purify proteins for screening and characterization studies.
• Design, execute, and troubleshoot experiments independently.
• Analyze, interpret, and present experimental data.
• Collaborate with multidisciplinary project teams to advance discovery programs.
• Document findings and communicate results effectively.
• Assist in training colleagues and sharing technical expertise when needed.
• Work under supervision to design, execute, analyze, interpret and troubleshoot scientific experiments in biochemistry and molecular biology.
• Accurately maintain written reports and present results in an organized and timely manner to research team.
• Communicate effectively with peers and supervisors, foster teamwork and contribute to collaborative efforts.
• Strong commitment to quality in research and presentation.

Benefits

• Employer Contributed Retirement Plan – Depending on eligibility, employees receive an employer contributed retirement plan (no employee contribution required) and the option to contribute to a 403(b) using your own pre or post-tax dollars.
• Full suite of Health and Welfare plans including four medical plan options (including an HSA available option), dental, vision, life insurance, disability, EAP and more.
• Access to Flexible Spending Accounts (Medical/Dependent Care).
• Competitive vacation and sick leave policies.
• Free, on-site parking.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level