RESEARCH ASSISTANT I
About The Position
Sanford Burnham Prebys is much more than a research facility and hub for innovation; it’s a vibrant global community of talented scientists and researchers from over 30 countries. This worldwide representation enriches our perspectives and enhances our creative approach to solving complex scientific challenges. We strive to be leaders not only in biomedical research but also in creating an environment where excellence thrives through collaboration across cultures and backgrounds. Our mission is to advance the biomedical sciences by cultivating the next generation of scientific leaders, providing meaningful opportunities for researchers of all backgrounds to learn, innovate, and make breakthrough discoveries that improve human health. Together, we translate science into health. The duties and responsibilities contained in the job description are intended to be examples of the accountabilities for which the person in the position will demonstrate competency through performance. The job description is not intended to be an all-inclusive list. Duties and responsibilities are subject to change and other duties may be assigned as necessary. Position Summary: The Research Assistant I will work in the Colas Lab supporting the RILPL1 project, which investigates how RILPL1 regulates the p53–MyoD axis to control muscle cell identity, hypertrophy, and myofiber size in cardiac and skeletal muscle. Work spans in vitro assays (myoblast/myotube culture, siRNA/shRNA-mediated knockdown, hypertrophy assays, and immunofluorescence-based myofiber size analysis) and in vivo work (mouse colony maintenance, genotyping, tissue collection, and histology) supporting ongoing interactome and pathway analyses. The Research Assistant will be learning new technologies, as well as applying existing knowledge to procedures and bench-work.
Requirements
- Bachelor’s degree in one of the biological science or related studies OR equivalent education, training and/or experience from which comparable knowledge, skills and abilities have been attained is required.
- Work independently as well as in a team environment.
- Be responsible and have strong time management skills.
- Able to analyze and resolve issues of moderate complexity.
- Possess strong attention to detail and organizational skills.
Nice To Haves
- Prior lab experience is a plus
- Experience with mammalian cell culture
- Mouse handling/husbandry
- Immunofluorescence or histology
- Standard molecular biology techniques (PCR, Western blot)
- IACUC training will be provided if not already completed.
Responsibilities
- Performs cell culture, siRNA/shRNA transfection, and hypertrophy assays in myoblast and myotube models, and processes mouse tissue for histology and myofiber size analysis.
- Keeps written records of experiments and data organization.
- Troubleshoots problems and develops solutions to technical problems of moderate to high scope using independent thinking, literature, and colleagues as resources to solve problems.
- Provides interpretation and analysis of RILPL1 project data (imaging, qPCR, Western blot).
- Maintains various reagent collections and inventories, and orders lab supplies as needed.
Benefits
- The expected hiring range for this position is $20.42 - $25.52 commensurate with relevant experience.
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
