Regional Sales Director, New England Region

Amylyx Pharmaceuticals • Cambridge, MA

1d • Onsite

About The Position

Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS). Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply. The Regional Sales Director is a first-line commercial leader responsible for building, leading, and developing a high-performing field team focused on post-bariatric hypoglycemia (PBH). This opportunity includes building and leading a team of highly motivated and accountable Territory Business Managers. Regional Sales Directors will work closely with their teams to advance PBH disease-state education and deepen understanding of the diagnosis and referral journey. This leader will execute national strategy into a focused regional plan and establish clear priorities. Success requires strong clinical and business acumen, disciplined execution, and the ability to navigate the complex diagnosis, referral, treatment, reimbursement, and patient-support pathways associated with a rare metabolic condition. This opportunity is based in New England and incumbents for this role should reside within the region.

Requirements

• Bachelor’s degree required; advanced degree preferred.
• 10+ years of progressive pharmaceutical or biotechnology commercial experience, including at least 3 years of successful field sales leadership and people management; equivalent combinations of education and experience will be considered.
• Demonstrated success in rare disease, endocrinology, metabolic disease, or another specialty market involving complex diagnosis, referral, treatment, reimbursement, and patient-support pathways.
• Proven record of recruiting and developing talent, leading through change, setting high standards, and delivering results through others in a compliant manner.
• Ability to translate enterprise and brand priorities into clear regional and territory plans, measurable objectives, and consistent field execution.
• Strong business and analytical acumen, including experience using CRM, market, account, and performance data for opportunity assessment, resource allocation, and decision-making.
• Track record of effective matrix leadership with Marketing, Medical Affairs, Market Access, Patient Services, Commercial Operations, Training, and Compliance partners.
• Excellent communication, coaching, influencing, and relationship-management skills, with the judgment and adaptability to operate in an evolving pre-launch and launch environment.
• Valid driver’s license and ability to meet the travel requirements of the role.

Nice To Haves

• Experience building or scaling a field team and leading launch-readiness or product-launch execution in a rare disease or specialty market.
• Knowledge of bariatric surgery care pathways, endocrinology, hypoglycemia, specialty pharmacy, reimbursement, and patient-support services.
• Established understanding of the healthcare landscape, including priority health systems, integrated delivery networks, and referral networks.

Responsibilities

• Recruit, hire, onboard, lead, coach, and retain a high-performing team of field sales professionals; establish clear expectations, individualized development plans, and succession readiness.
• Own the regional business plan, translating PBH brand priorities into territory strategies, account plans, customer-engagement objectives, resource allocation, and measurable standards of execution.
• Establish a disciplined operating rhythm that includes field coaching, business reviews, performance tracking, opportunity planning, and timely course correction to ensure performance objectives are met or exceeded.
• Use CRM data, market intelligence, account insights, referral-network dynamics, and leading indicators to identify opportunities and risks, prioritize resources, and improve regional performance.
• Spend substantial time in the field observing customer engagement and providing timely, behavior-based coaching on clinical dialogue, pre-call planning, account strategy, reimbursement, patient-support resources, and execution excellence.
• Set clear performance expectations, recognize strong performance, and address capability or execution gaps through direct feedback, documented development actions, and appropriate performance management.
• Develop productive relationships with priority health systems, bariatric programs, endocrinology and metabolic care teams, key experts, and other stakeholders involved in PBH diagnosis, referral, treatment, access, and patient support.
• Manage the regional budget and other company resources responsibly, ensuring regional investments align with strategic priorities and company policies.
• Model Amylyx values and maintain the highest standards of ethics, compliance, accountability, inclusion, and respect for patients and caregivers.

Benefits

• The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity. Estimated Pay Range $225,000 - $253,000 USD

What This Job Offers

• Job Type: Full-time
• Career Level: Senior