R&D Scientist III

Thermo Fisher Scientific • Fremont, CA

5d • $100,000 - $133,300 • Onsite

About The Position

As part of the Thermo Fisher Scientific team, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. Contribute to the development of high-quality assay reagents by designing and executing synthetic routes for haptens, adducts, and related intermediates. Apply your hands-on expertise in organic synthesis, bioconjugation, and analytical chemistry to deliver consistent, high-performance materials that support diagnostic innovation.

Requirements

• MS in Chemistry, Biochemistry, or related field with 4+ years of relevant laboratory experience, or PhD with 2–3 years of experience in organic synthesis, bioconjugation, or related discipline.
• Practical experience in organic synthesis, purification, and characterization of small molecules or conjugates.
• Proficiency in synthetic design, purification (chromatography), and analytical tools (LC-MS, HPLC, UV-Vis, NMR).
• Demonstrated proficiency and extensive laboratory experience in conjugation chemistry and protein modification.
• Excellent organizational, communication, and problem-solving skills.
• Ability to work independently and collaboratively in a fast-paced R&D environment.
• Strong documentation and data interpretation skills, aligned with quality and safety standards.
• Ability to adhere to strict safety protocols and procedures to ensure a safe working environment.
• Must be legally authorized to work in the United States without sponsorship.
• Successful completion of a background check, including screening for any history related to controlled substances.

Nice To Haves

• Exposure to protein conjugation and analytical characterization techniques preferred.
• Experience with immunoassay or diagnostic reagent development is an advantage.

Responsibilities

• Perform synthesis, purification, and characterization of haptens, adducts, and conjugates.
• Execute protein conjugation reactions and validate product integrity through analytical techniques (HPLC, MS, UV, etc.).
• Collaborate with cross-functional teams to transfer materials and ensure reagent quality.
• Troubleshoot and optimize synthetic or conjugation workflows for improved yield and consistency.
• Maintain laboratory documentation and support continuous process improvement.
• Handle, manage, and oversee controlled substances, ensuring compliance with all relevant regulations and guidelines.
• Ensure proper safety protocols and protective measures are followed when exposed to controlled substances.

Benefits

• Competitive remuneration
• Annual incentive plan bonus
• Healthcare
• A choice of national medical and dental plans, and a national vision plan, including health incentive programs
• Employee assistance and family support programs
• Commuter benefits
• Tuition reimbursement
• At least 120 hours paid time off (PTO)
• 10 paid holidays annually
• Paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave)
• Accident and life insurance
• Short- and long-term disability
• Competitive 401(k) U.S. retirement savings plan
• Employees’ Stock Purchase Plan (ESPP)

What This Job Offers

• Job Type: Full-time
• Career Level: Senior