R&D Molecular Diagnostics Technician (Fountain Valley, CA)

Antech Diagnostics•Fountain Valley, CA

1d•Onsite

About The Position

The R&D Molecular Diagnostics Technician performs molecular diagnostic protocols, troubleshoots escalated diagnostic cases, supports continuous improvement, and creates quality-control criteria for novel assays. This is a dynamic, interactive, fast-paced role in molecular diagnostics research and development that calls for a proactive, problem-solving approach. The position works under close to moderate supervision, with limited latitude for independent judgment, and partners with associates across departments to support shared business goals. The technician performs and analyzes molecular testing, designs and conducts experiments to investigate reagents, tests, protocols, and assay design, and supports assay improvements by investigating escalated clinical cases and identifying new genotypes. Additional duties include preparing color-compensation reagents, reviewing experiments, supporting transitions of R&D protocols to QA and manufacturing, maintaining quality databases and filing systems, conducting statistical and stability analyses, and maintaining laboratory equipment and supplies. The role may require travel up to 25% and extended hours. The laboratory environment may include biohazards and potentially hazardous chemicals; required PPE mitigates exposure risks.

Requirements

Bachelor’s degree in Molecular Biology, Biology, Molecular Sciences, Biotechnology, Biochemistry, Immunology, or a related science field.
At least 1–3 years of PCR-related laboratory experience.
At least 1–3 years of quality assurance experience.
Laboratory skills and experience designing and running experiments, interpreting data, and troubleshooting molecular assays and instruments.
General science background, including cellular biology, basic nucleic acid biochemistry, and biology of disease.
Understanding of molecular design.
Analytical skills related to scientific and laboratory activities.
Attention to detail and problem-solving abilities.
Ability to stay organized and multitask in a fast-paced R&D environment.
Ability to work independently and as part of an interactive team.
Strong verbal and written communication skills.
Knowledge of Good Clinical Practice (GCP) and Good Laboratory Practices (GLP), as appropriate.
Personal computer skills, including strong typing ability and proficiency with Microsoft Office (Excel, Word, and PowerPoint).
Fluency in English.
Ability to meet the described physical demands, including standing continuously for up to two hours and potentially lifting, moving, and carrying up to 50 pounds.

Nice To Haves

Graduate degree in Molecular Biology, Biology, Cell & Molecular Biology, Immunology, or a related science field.

Responsibilities

Follow and perform protocols for a variety of molecular diagnostic techniques.
Perform nucleic acid extraction, with emphasis on molecular diagnostic testing.
Perform and analyze real-time PCR (qPCR), digital droplet PCR (ddPCR), microarray- or bead-based array technologies, sequencing protocols, and other molecular protocols.
Design and conduct experiments investigating reagents, tests, protocols, and molecular assay design.
Investigate escalated clinical cases and identify new genotypes to support continuous improvement of molecular assays.
Create quality-control criteria for novel molecular assays and new reagent lots.
Prepare color-compensation kit reagents and review color-compensation experiments from multiple laboratories.
Assist with transitioning R&D protocols to QA and manufacturing departments.
Maintain the QA database and filing system.
Perform statistical analyses of data, including monitoring ISC QC failures and QuanPCR rates.
Establish reagent stability by designing and conducting stability studies.
Evaluate and report results to a supervisor.
Perform equipment maintenance and apply knowledge of laboratory equipment and procedures, quality control, and calibration.
Enter samples into the physical central sample collection and computer database.
Partner with associates across departments to advance shared business goals.
Cross-train and develop knowledge of multiple specialties within the department or laboratory.
Follow applicable SOPs, including safety and quality procedures.
Maintain a clean and organized work area and laboratory space.
Monitor supply inventory and restock as needed.
Participate in improving laboratory efficiency, quality, and cooperation.
Consult with senior peers to troubleshoot problems.
Participate in enterprise initiatives and special projects, and perform other duties as assigned.
Maintain reliable and dependable attendance and adhere to attendance-related policies and expectations.
Travel up to 25% of the time if required.