Apriori Bio: Protein Science Co-Op
About The Position
This position is open exclusively to current Northeastern University Co-Op students. Work Period: January 2027 to June 2027. This is a full-time, 40 hours per week position with 5 days in office. Join Our Innovative Team at Apriori Bio! Are you ready to be part of a pioneering biotech company on the frontline of developing solutions against rapidly evolving viruses like influenza and SARS-CoV-2? At Apriori Bio, we're creating a safer world through resilient vaccines and advanced antibody therapeutics using our cutting-edge Octavia™ platform. About Flagship Pioneering Apriori Bio was founded by Flagship Pioneering’s venture creation engine that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com. Flagship Pioneering Co-Op Program Welcome to the Flagship Pioneering Co-Op Program for the cohort dreaming big and taking courageous leaps. You’ll join fellow peers across our ecosystem of companies and learn firsthand how we build first-in-category companies. You’ll have access to enrichment sessions, a dedicated professional development track, and a mentor that help guide you toward your next step. By the end, you will carry on a meaningful project outcome, a genuine network, and a front-row view of how Flagship pioneers new ventures that change the world. The Role As a member of our protein science team, you’ll help turn computationally designed vaccine immunogens into well-characterized proteins. Our team produces antigens in multiple formats for antigen validation and in-vivo studies, and develops the assays used to characterize and functionally validate them.
Requirements
- Pursuing a BS or MS in Biochemistry, Bioengineering, Chemical Engineering, Molecular Biology, or a related field
- Hands-on laboratory experience (coursework or research), such as SDS-PAGE, solution preparation, and accurate pipetting
- Experience with mammalian cell culture and aseptic technique
- Strong organizational, record-keeping, and communication skills
Nice To Haves
- exposure to protein purification/chromatography or plate-based assays such as ELISA
Responsibilities
- Express recombinant vaccine antigens and antibodies in mammalian expression systems, including small-scale transient transfection and scale-up.
- Purify proteins using affinity and size-exclusion chromatography on ÄKTA systems.
- Characterize protein quality and stability using SDS-PAGE, analytical SEC, and thermal stability methods such as DSF.
- Contribute to the development and execution of binding and functional assays, including ELISA and bio-layer interferometry (BLI), to assess antigenicity against panels of monoclonal antibodies.
- Document experiments in our electronic lab notebook (Benchling) and present results at team meetings.
Benefits
- Compensation reflects the real work you take on.
- Strong co-ops are considered for future opportunities across Flagship and its portfolio companies, not just for this one role.
Stand Out From the Crowd
Upload your resume and get instant feedback on how well it matches this job.
What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Education Level
Associate degree
