Protein Analytics Scientist

Bristol Myers Squibb • Brisbane, CA

3d • $156,293 - $166,240 • Hybrid

About The Position

Bristol Myers Squibb Company is hiring a(n) Protein Analytics Scientist (in Brisbane, CA). This role involves distinguishing the primary, tertiary, and quaternary protein structure using a variety of characterization techniques such as mass spectrometry, liquid chromatography, and other analytical techniques. The scientist will analyze complex mass spectroscopic data sets derived from chemical foot printing, post-translational modification, de novo sequencing, and proteomic experiments. They will leverage expertise in protein characterization and mass spectroscopic expertise towards selection and optimization of therapeutic antibodies, conduct epitope mapping and crosslinking studies to classify protein-protein interactions and binding interfaces, and design and execute mass spectrometry-based proteomics studies. The role also includes performing structural characterization of antibody and protein therapeutics to support the selection of lead candidates, developing workflows to analyze and visualize complex proteomics datasets, and presenting data and analysis in written and oral form to project leaders and teams. Collaboration with cross-functional groups including Biology, Protein Expression/Purification, and Protein Engineering is essential.

Requirements

• PhD degree or foreign equivalent degree in Chemistry, Biochemistry, Biophysics, Pharmaceutical, Chemical Science, or a related field
• Two (2) years of related work experience as a Biochemist and Biophysicist or related occupation
• Two (2) years of experience with/in: Characterizing protein structure including molecular weight, aggregation state, glycan structure, and post-translational modification
• Two (2) years of experience with/in: Protein and peptide mass spectrometry
• Two (2) years of experience with/in: Programming and developing computational algorithms and software for mass spectrometry data processing and visualization
• Two (2) years of experience with/in: Developing and running multiple types of protein characterization assays using cutting edge technologies such as LC-MS, SEC-MALS, glycan analysis, and capillary electrophoresis and hydrophobic interaction chromatography.

Responsibilities

• Distinguish the primary, tertiary, and quaternary protein structure using a variety of characterization techniques such as mass spectrometry, liquid chromatography, and other analytical techniques.
• Analyze complex mass spectroscopic data sets derived from chemical foot printing, post-translational modification, de novo sequencing, and proteomic experiments.
• Leverage expertise in protein characterization and mass spectroscopic expertise towards selection and optimization of therapeutic antibodies.
• Conduct epitope mapping and crosslinking studies to classify protein-protein interactions and binding interfaces.
• Design and execute mass spectrometry-based proteomics studies.
• Perform structural characterization of antibody and protein therapeutics to support the selection of lead candidate.
• Develop workflows to analyze and visualize complex proteomics datasets.
• Present data and analysis in written and oral form to project leaders and teams.
• Collaborate with cross functional groups including Biology, Protein Expression/Purification, and Protein Engineering.

Benefits

• annual discretionary bonus
• healthcare
• leave benefits
• retirement benefits
• Health Coverage: Medical, pharmacy, dental, and vision care.
• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
• Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays
• Based on eligibility, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree