Project Manager, Discovery & Preclinical Development

Protagonist Therapeutics • Newark, NJ

2d

About The Position

We are seeking a highly organized, driven, collaborative, and scientifically grounded Project Manager to join our growing R&D team. In this pivotal role, you will be responsible for orchestrating and managing cross-functional drug discovery and preclinical development programs. The ideal candidate possesses a deep understanding of the drug discovery process and has a proven track record of managing global Contract Research Organizations (CROs) while seamlessly integrating internal and external efforts to drive therapeutics toward the clinic.

Requirements

• Deep, practical knowledge of the end-to-end drug discovery and preclinical development process (through lead optimization, Candidate selection and IND-enabling studies).
• 3+ years of dedicated project management experience within the biotech or pharmaceutical industry, specifically focusing on early-stage discovery and preclinical R&D.
• Demonstrated experience working with and managing external vendors and international CRO networks (specifically in the US, China, and India).
• Exceptional written and verbal communication skills. Ability to translate complex scientific data into actionable project updates for key stakeholders and executive leadership.
• Bachelor's or Master's degree in a relevant scientific discipline (Chemistry, Biology, Pharmacology, or related field).

Nice To Haves

• Ph.D. or equivalent experience is highly preferred.
• PMP (Project Management Professional) certification is a strong plus.

Responsibilities

• Develop, maintain, and track comprehensive project plans and timelines for early discovery through preclinical/IND-enabling stages.
• Proactively identify risks, resource constraints, and critical path activities.
• Serve as the central hub of communication and operational execution across all internal discovery functions, including: Medicinal/Synthetic Chemistry, Biology (In vitro/Assay Development), DMPK (Drug Metabolism and Pharmacokinetics), In Vivo Pharmacology, Formulation and CMC, Toxicology.
• Timely reporting of deadlines and key program deliverables; ensure cross-functional study reports and any other documents required for regulatory purposes are completed and QC’d on time.
• Act as the primary point of contact for external partners. Source, onboard, and manage CROs based in the US, China, and India. Monitor CRO performance, ensure timely delivery of high-quality data, manage budgets, and resolve any operational bottlenecks.
• Facilitate regular project team meetings, create agendas, document minutes, and track action items to ensure alignment with corporate goals and therapeutic milestones.
• Continuously evaluate and improve project management workflows, reporting tools, and communication streams between internal teams and external vendors.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level