Production Chemist - Torrance

PolyPeptide US•Torrance, CA

8d•Onsite

About The Position

PolyPeptide is seeking Production Chemists at multiple levels (I, II, and III) to support the manufacture of high-quality Active Pharmaceutical Ingredients (APIs) in a cGMP-regulated environment. These roles are critical to our mission of delivering safe, effective, and on-time pharmaceutical products to patients worldwide. Whether you are early in your career or an experienced chemist ready to lead, we offer a clear growth path, hands-on manufacturing experience, and the opportunity to work with advanced peptide synthesis and purification technologies.

Requirements

Bachelor’s degree in a scientific discipline or equivalent
High School Diploma with significant GMP manufacturing experience may be considered (Chemist I)
0–2 years of relevant experience (peptide manufacturing preferred) (Chemist I)
3+ years of relevant experience in a regulated environment (Chemist II)
5+ years of relevant experience with demonstrated leadership and technical expertise (Chemist III)
Peptide synthesis and purification (HPLC)
cGMP documentation and compliance
Safe handling of hazardous chemicals and reagents
Strong communication, teamwork, and time management
Problem-solving and continuous improvement mindset

Responsibilities

Execute batch production records (BPRs) accurately and in compliance with SOPs and GxP requirements
Operate and monitor chemical processes including reactors, drying systems, purification HPLCs, and lyophilization
Perform in-process controls (IPCs) and interpret analytical results (e.g., HPLC, ninhydrin tests)
Ensure proper material handling, inventory management, and ERP documentation following ALCOA+ principles
Maintain high standards of safety, cleanliness, PPE usage, and 5S practices
Communicate effectively with cross-functional teams including QA, QC, Maintenance, Engineering, and Supply Chain
Troubleshoots process deviations, supports investigations, and assists with CAPAs and quality documentation (Chemist II & III)
Trains and mentors Chemist I team members (Chemist II & III)
Participates in process improvements, tech transfers, and scale-up activities (Chemist II & III)
Acts as a subject matter expert (SME) for processes and equipment (Chemist III)
Makes operational “go/no-go” decisions with Quality and leadership (Chemist III)
Leads troubleshooting, process optimization, and mentoring of Chemist I & II staff (Chemist III)
Supports production planning, forecasting, and continuous improvement initiatives (Chemist III)