Process Development Upstream Scientist

Wheeler Bio • Oklahoma City, OK

1d

About The Position

As a Process Development Scientist, you will support the development, optimization, and scale-up of mammalian upstream bioprocesses for the manufacture of biologic drug substances. You will contribute to the design and execution of laboratory experiments, data analysis, and technical documentation.

Requirements

• Bachelor's, master's or PhD degree in Chemical Engineering, Biochemistry, Biotechnology, Biology, or related field.
• 4-8 years of hands-on experience in a bioprocessing or biopharmaceutical development environment (academic or industrial); some education qualifications may substitute for some years of experience.
• Experience with suspension mammalian cell culture and stirred tank bioreactors is required.
• Strong analytical and problem-solving skills.
• Good written and verbal communication skills.
• Ability to work both independently and in a collaborative team environment.

Nice To Haves

• Experience in a CDMO environment is preferred.
• Knowledge of protein purification and analytical techniques is a plus.
• Understanding of cGMP, GLP, or other regulatory standards (preferred).

Responsibilities

• Perform laboratory experiments to support mammalian upstream (cell culture) process development.
• Assist in the optimization of bioprocess parameters for yield, purity, and product quality.
• Support scale-up and technology transfer of processes to manufacturing or pilot facilities.
• Prepare buffers, media, and other solutions according to SOPs and protocols.
• Operate and maintain flask and bioreactor equipment.
• Collect, analyze, and interpret experimental data; maintain accurate lab records and electronic notebooks.
• Present findings in internal and client meetings and contribute to technical reports and regulatory documentation.
• Complete Root Cause Analyses as needed.
• Follow all safety, quality, and compliance requirements.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree
• Number of Employees: 11-50 employees