Process Development Senior Scientist

Amgen • Cambridge, MA

1d • $123,777 - $167,463 • Onsite

About The Position

Join Amgen’s Mission of Serving Patients. At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Process Development Senior Scientist What you will do Let’s do this. Let’s change the world. In this vital role you will join the Drug Substance Technologies – Synthetics (DSTS) group within Process Development at our Cambridge, Massachusetts site. The DSTS organization is responsible for the invention, development, and implementation of innovative drug substance manufacturing processes and technologies that advance Amgen’s growing portfolio of small molecule and hybrid therapeutics. Our process chemists leverage deep expertise in organic chemistry to design efficient synthetic routes and scalable chemical processes that support drug substance manufacturing from early through late-stage development. The successful candidate will be a collaborative, scientifically driven individual with strong expertise in organic chemistry, a passion for innovation, and a demonstrated record of scientific achievement.

Requirements

• Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable] completed by August 2026 OR Master’s degree and 3 years of Scientific experience OR Bachelor’s degree and 5 years of Scientific experience

Nice To Haves

• Ph.D. in Organic Chemistry with expertise in total synthesis, reaction methodology, mechanistic chemistry, and/or process development
• Postdoctoral experience in academia or the pharmaceutical/biotechnology industry
• Experience with ADC, peptides
• Demonstrated track record of scientific innovation through peer-reviewed publications, patents, and/or conference presentations
• Strong problem-solving skills and ability to work effectively in a dynamic, interdisciplinary research environment
• Excellent written and verbal communication skills, with strong organizational and time management abilities
• Ability to manage multiple priorities and drive complex projects to completion
• A research summary submitted with the CV is strongly encouraged

Responsibilities

• Design and develop synthetic routes and scalable chemical processes for the manufacture of synthetic and hybrid drug substances
• Develop safe, robust, efficient, and cost-effective manufacturing processes suitable for clinical and commercial production
• Advance enabling technologies that accelerate pharmaceutical development and improve sustainability, efficiency, and process robustness
• Support cGMP manufacturing activities and assist with technology transfer efforts to internal manufacturing sites and external contract manufacturing organizations (CMOs)
• Build process understanding through experimentation, process characterization, modeling, and data analysis to ensure consistent process performance
• Contribute to cross-functional drug substance development teams by providing technical expertise, experimental data, scientific recommendations, and clear documentation
• Collaborate across disciplines to support regulatory filings and author technical sections of regulatory documentation
• Stay current with advances in synthetic organic chemistry, process chemistry, and related technologies, and apply new scientific insights to ongoing programs
• Effectively collaborate within multidisciplinary teams that include chemists, engineers, analytical scientists, and other technical experts
• Independently manage project activities and deliver high-quality results within established timelines

Benefits

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible

What This Job Offers

• Job Type: Full-time
• Career Level: Senior