Process Development Co-op (Spring 2027)
About The Position
Wave Life Sciences is a biotechnology company focused on unlocking the broad potential of RNA medicines to transform human health. Our RNA medicines platform, PRISM, combines multiple modalities, chemistry innovation and deep insights in human genetics to deliver scientific breakthroughs that treat both rare and prevalent disorders. Our toolkit of RNA-targeting modalities including RNAi silencing and RNA editing provides us with unmatched capabilities for designing and sustainably delivering candidates that optimally address disease biology. Our diversified pipeline is focused on our obesity, alpha-1 antitrypsin deficiency and PNPLA3 I148M liver disease programs and includes clinical programs for Duchenne muscular dystrophy and Huntington’s disease, as well as several preclinical programs utilizing our versatile RNA medicines platform. Driven by the calling to “Reimagine Possible”, we are leading the charge toward a world in which human potential is no longer hindered by the burden of disease. Wave Life Sciences seeks a highly motivated co-op students to join its team of scientists in Lexington, Massachusetts. The co-op student will gain exposure to areas of oligonucleotide synthesis, purification, and analysis. Co-ops will be trained in a variety of laboratory techniques and instrumentation, making this an excellent learning opportunity. This is an ideal position for any student, including those looking for their first co-op, with strong organizational skills and attention to detail who thrives in a team-oriented, fast-paced and cross-disciplinary biotech environment.
Requirements
- Present experimental data in team meetings
- Eager to learn about instrumentation and work with new technology
- Following the lab safety protocols including use of PPEs
Nice To Haves
- Organic chemistry or biochemistry laboratory experience is preferred.
Responsibilities
- Assist in the upstream and downstream development of oligonucleotides
- Preparation of synthesis reagents for solid phase oligonucleotide synthesis by weighing organic compounds and preparing reagents
- Independently prepare buffer solutions of specified molarity for purification of oligonucleotides
- Assist in the operation of AKTA systems and be able to learn and work on UNICORN software
- Assist in running desalting operations on Sartoflow TFF systems
- Prepare and submit samples on analytical systems such as UPLC and LCMS and conduct analysis
- Maintain a detailed report of experimental procedures and findings in electronic lab notebooks
- Use of pH meter, Nanodrop to record data
- Use of MS Excel is preferred
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What This Job Offers
Career Level
Intern
Education Level
No Education Listed
