Process Development Associate Scientist

Amgen•Cambridge, MA

1d•$90,443 - $122,363

About The Position

The Process Development Associate Scientist develops cell culture and purification manufacturing processes for Amgen’s late-stage pipeline, with a focus on recombinant proteins. The work aims to improve production yields, evaluate process robustness through process characterization, and transfer processes to manufacturing. Other experiments may include facility fit and raw material evaluation. The role contributes to drug substance process development in a team environment. It involves mammalian cell culture experiments at different scales using shake flasks and bioreactors, as well as purification experiments—primarily filtration and chromatography—at bench and pilot scale as needed. The Associate Scientist documents experimental data in lab notebooks, analyzes and presents data to the team, authors technical reports, supports regulatory filings as needed, and contributes to technology development projects focused on continuous improvements in reliability and efficiency.

Requirements

Master’s degree; or a bachelor’s degree and 3 years of Process Development experience.

Nice To Haves

Relevant hands-on laboratory experience in cell culture or protein purification.
Attention to detail and critical thinking ability.
Experience in Design of Experiments and statistical analysis.
Strong oral and written communication skills.
Self-motivation and strong organization skills.
Strong interpersonal skills and ability to work in a dynamic, collaborative environment.

Responsibilities

Develop cell culture and purification manufacturing processes for recombinant proteins.
Improve production yields and evaluate process robustness through process characterization.
Transfer processes to manufacturing.
Conduct experiments such as facility fit and raw material evaluation.
Contribute to drug substance process development in a team environment.
Execute mammalian cell culture experiments at different scales in shake flasks and bioreactors.
Execute purification experiments, mainly filtration and chromatography, at bench and pilot scale as needed.
Document experimental data in lab notebooks.
Analyze data and present it to the team.
Author technical reports and support regulatory filings as needed.
Contribute to technology development projects to improve reliability and efficiency.

Benefits

Health and welfare plans for staff and eligible dependents.
Retirement and savings plans with opportunities to save toward retirement or other goals.
Comprehensive employee benefits package including a Retirement and Savings Plan with generous company contributions.
Group medical, dental, and vision coverage.
Life and disability insurance.
Flexible spending accounts.
Discretionary annual bonus program, or a sales-based incentive plan for field sales representatives.
Stock-based long-term incentives.
Award-winning time-off plans.
Career development opportunities.
Flexible work models where possible.