Principal Solutions Architect - PLM & Digital Thread

MESO SCALE DIAGNOSTICS, LLC. • Rockville, MD

1d • Hybrid

About The Position

The Principal Solutions Architect – PLM & Digital Thread is a strategic technical leader responsible for architecting and implementing Siemens Teamcenter X as the core of MSD’s digital thread. This role also involves designing and maintaining integrations between PLM, Manufacturing Execution Systems (MES), and JD Edwards EnterpriseOne (JDE) ERP to ensure data continuity across the product lifecycle. Additionally, the position owns the ongoing operational stability, support, and continuous improvement of these systems. The role works closely with the Digital Thread Process Lead to translate strategy and process requirements into scalable, cloud-based technical solutions, requiring deep PLM domain expertise and experience in regulated environments.

Requirements

• Bachelor’s degree in Computer Science, Engineering, or a related field.
• 7+ years of hands-on experience with Siemens Teamcenter PLM, including implementation, configuration, upgrading, and administration across multiple versions and releases.
• Proven track record as a Solutions Architect or senior PLM technical leader, with demonstrated experience implementing digital thread processes in partnership with business process owners.
• Demonstrated experience designing integrations between PLM and downstream enterprise systems (MES and/or ERP).
• In-depth knowledge of core Teamcenter modules: Active Workspace, BMIDE, workflow design, change management, and data models.
• Experience implementing PLM in FDA-regulated or GxP environments, including computer system validation and 21 CFR Part 11 compliance.
• Transformational experience: demonstrated history of leading or significantly contributing to enterprise-scale PLM implementations that changed how an organization operates.

Nice To Haves

• Direct experience with Teamcenter X (cloud/SaaS PLM).
• Consulting experience across multiple customers and implementations in the life sciences industry.
• Experience architecting integrations specifically with JD Edwards EnterpriseOne (JDE).
• Working knowledge of MES principles and manufacturing data flows, including work order management, shop floor routing, and production traceability in both discrete and process manufacturing.
• Familiarity with digital thread concepts: Production configuration management, routers, BOM lifecycle management, document management, change management and closed-loop quality integration across enterprise systems.
• Experience supporting ISO 9001 quality management systems.

Responsibilities

• Architect, configure, and implement PLM solutions in Teamcenter X to support engineering, quality, and manufacturing processes, focusing on establishing a unified digital thread.
• Partner with the Digital Thread Process Lead to translate process requirements into Teamcenter X configurations, workflows, and integrations.
• Serve as the subject matter expert on Siemens Teamcenter X, administering the platform, staying current with SaaS release cycles, and driving adoption of best practices.
• Design and maintain integrations between Teamcenter X, MES platforms, and JD Edwards EnterpriseOne (JDE) to ensure data integrity and process continuity.
• Design contextually relevant MES integrations covering work order execution, shop floor routing, material tracking, and production traceability.
• Support data-flow design between ERP and PLM/MES layers, including manufacturing, procurement, quality management, and inventory modules in JDE.
• Implement and maintain integrations with CAD tools, laboratory systems, and other enterprise applications.
• Provide ongoing operational support for Teamcenter X and its integrated systems, including incident response, break/fix resolution, user support, system health monitoring, and vendor escalation coordination.
• Troubleshoot and resolve software issues across the PLM and integration stack.
• Drive continuous improvement of the PLM platform and integration architecture in alignment with MSD’s digital transformation roadmap.
• Lead architecture discussions and design technical solutions to support business partners’ digital transformation initiatives.
• Collaborate with cross-functional teams and business/functional analysts to gather requirements, create specifications, and deliver validated solutions meeting 21 CFR Part 11 and GxP requirements.
• Collaborate with business process owners and the project management office to define implementation plans, manage priorities, and align PLM roadmap milestones.
• Ensure testing is appropriate and complete, business process procedures are accurate, and all configuration and validation standards are adhered to.
• Coach team members to build internal PLM technical capability and reduce dependency on external resources.

Benefits

• Medical coverage
• Dental coverage
• Vision coverage
• Prescription benefits
• 401(k) plan with company matching
• Flexible spending accounts
• Company-paid short-term disability insurance
• Company-paid long-term disability insurance
• Group life insurance
• Accidental death and dismemberment insurance
• Paid vacation
• Paid sick leave
• Paid holidays
• Paid parental leave
• Employee assistance program
• Fitness club membership contribution
• Pet insurance
• Identity theft protection
• Home and auto insurance discounts
• Optional supplemental life insurance

What This Job Offers

• Job Type: Full-time
• Career Level: Principal