Principal Scientist

ICON plc • Lenexa, KS

10d • Onsite

About The Position

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster. As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers. We are excited to be seeking a new Research Scientist at ICON in Lenexa, Kansas (KS). The Research Scientist will lead and conduct scientific research aimed at advancing clinical trials and developing innovative therapies. You will manage sponsor programs, shape assay strategies, and provide expertise for new and complex modalities. We are seeking candidates with robust method development and knowledge in science for new biological modalities.

Requirements

• PhD or equivalent degree in a relevant scientific field such as biology, chemistry, pharmacology, or clinical research.
• MS degrees considered with proven LC/MS/MS method development experience in the pharmaceutical or clinical research industry.
• Experience in conducting research within the clinical or pharmaceutical industry, with a proven track record of managing scientific projects.
• Strong analytical skills and expertise in data interpretation and statistical analysis.
• Excellent written and verbal communication skills, with the ability to present complex scientific information to both technical and non-technical audiences.
• Willingness to travel as required (approximately 5%)
• Having the legal right to work in the country where the role is based.

Responsibilities

• Method development and validation for testing preclinical and clinical specimens using LC/MS/MS analytical methods.
• Oversee transfer robust LC/MS/MS methods for small molecules, radiolabeled compounds and biologics for bioanalytical testing.
• Independently direct development and validation of new LC/MS/MS assays using appropriate methods such as (but not limited to) Tomtec, Hamilton, Kingfisher, Integra Assist plus, etc.
• Ensure robust LC/MS/MS methods are developed for successful method validation of both small molecules, radiolabeled analytes and biologics such as ADCs, oligonucleotides, mAb, etc.
• Review data presentations for accuracy and clarity prior to sharing with sponsors
• Provide support to Laboratory Operations staff regarding assay quality, expected results, troubleshooting and data review
• Provide technical input for ICON Marketing collateral, attend conferences, publish papers in the peer-reviewed literature
• Drive new business by consulting with sponsors on assay requirements for new projects
• Collaborate with inter-departmental functions to write and review validation plans, reports and SOP’s
• Lead assay transfers to other ICON lab locations

Benefits

• Competitive base salary and performance related incentives
• Health and wellbeing programmes including medical, dental, and vision coverage where applicable
• Retirement and pension plans
• Life assurance and disability coverage
• Employee assistance programmes and wellbeing resources
• Learning and development opportunities through structured training and career pathways

What This Job Offers

• Job Type: Full-time
• Career Level: Principal
• Education Level: Ph.D. or professional degree