Principal Scientist – NGS/Genomics and Bioinformatics

Thermo Fisher Scientific • Richmond, VA

2d • Onsite

About The Position

This is a fully onsite role based in the bioanalytical laboratory in Richmond, VA. Thermo Fisher Scientific's PPD® Laboratory Services team is seeking a Principal Scientist to lead the strategy, design, and implementation of NGS sequencing platforms. This role is pivotal in defining the next phase of the laboratory’s molecular innovation, integrating sequencing, proteomics, and spatial transcriptomics to deliver comprehensive multi-omics solutions. The company's mission is to enable customers to make the world healthier, cleaner, and safer, contributing to life-changing therapies through clinical trials globally. The position offers an opportunity to make a significant impact on patient health outcomes.

Requirements

• Bachelor's degree or equivalent and relevant formal academic / vocational qualification with 12+ years’ experience, OR Master's degree with 10+ years’ experience, OR PhD with 8+ years’ experience
• Demonstrated leadership in launching or managing NGS and spatial sequencing platforms and analysis
• Ultima and/or Illumina NGS - MUST HAVE
• Proven track record of cross-functional scientific leadership and technical innovation
• Expert knowledge of sequencing chemistry, data QC, and assay validation, data analysis/bioinformatics
• Experience integrating sequencing with proteomics or other omics technologies
• Strong communication and external collaboration skills
• Strategic mindset with ability to identify and implement new technologies
• Demonstrated success mentoring staff and building scientific teams
• Must be legally authorized to work in the United States without sponsorship
• Must be able to pass a comprehensive background check, which includes a drug screening

Responsibilities

• Oversee setup, qualification, and validation of the Ultima and/or Illumina NGS system
• Lead evaluation and implementation of genomics and proteomics technologies (NextGen Sequencing (WGS, RNASeq, targeted sequencing), spatial sequencing (10x Genomics Chromium, Visium, Xenium), O-Link HT, NuLISA)
• Define and execute the sequencing strategy for the lab, aligning with organizational and client objectives
• Mentor scientists and analysts in NGS workflows, QC, and data interpretation including bioinformatics support
• Partner with automation, bioinformatics, and proteomics teams for multi-omics integration
• Represent the lab in vendor partnerships, conferences, and technical collaborations

Benefits

• Resources needed to achieve individual career goals
• Opportunity to take science a step beyond through research, development and delivery of life-changing therapies
• Rewarding careers
• Reasonable accommodation for individuals with disabilities to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees