Principal Scientist – NGS/Genomics and Bioinformatics
About The Position
This is a fully onsite role based in our bioanalytical laboratory in Richmond, VA. At Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale, enabling customers to make the world healthier, cleaner and safer. The PPD® Laboratory Services team directly impacts patient health through the expertise of scientists, industry thought-leaders and therapeutic experts. We are seeking a Principal Scientist to lead the strategy, design, and implementation of our NGS sequencing platforms. This role defines the next phase of our laboratory’s molecular innovation—combining sequencing, proteomics, and spatial transcriptomics to deliver integrated multi-omics solutions.
Requirements
- Bachelor's degree or equivalent and relevant formal academic / vocational qualification
- Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 12+ years’) or equivalent combination of education, training, and experience
- OR Masters degree and previous experience that provides the knowledge, skills, and abilities to perform the job (comparable 10+ year)
- OR PhD and previous experience that provides the knowledge, skills, and abilities to perform the job (comparable 8+ year)
- In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role
- Demonstrated leadership in launching or managing NGS and spatial sequencing platforms and analysis
- Ultima and/or Illumina NGS - MUST HAVE
- Proven track record of cross-functional scientific leadership and technical innovation
- Expert knowledge of sequencing chemistry, data QC, and assay validation, data analysis/bioinformatics
- Experience integrating sequencing with proteomics or other omics technologies
- Strong communication and external collaboration skills
- Strategic mindset with ability to identify and implement new technologies
- Demonstrated success mentoring staff and building scientific teams
- Must be legally authorized to work in the United States without sponsorship
- Must be able to pass a comprehensive background check, which includes a drug screening
Responsibilities
- Oversee setup, qualification, and validation of the Ultima and/or Illumina NGS system
- Lead evaluation and implementation of genomics and proteomics technologies (NextGen Sequencing (WGS, RNASeq, targeted sequencing), spatial sequencing (10x Genomics Chromium, Visium, Xenium), O-Link HT, NuLISA)
- Define and execute the sequencing strategy for the lab, aligning with organizational and client objectives
- Mentor scientists and analysts in NGS workflows, QC, and data interpretation including bioinformatics support
- Partner with automation, bioinformatics, and proteomics teams for multi-omics integration
- Represent the lab in vendor partnerships, conferences, and technical collaborations
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What This Job Offers
Job Type
Full-time
Career Level
Principal
Education Level
Ph.D. or professional degree
Number of Employees
5,001-10,000 employees
