Bioinformatics Scientist

Plasmidsaurus•San Francisco, CA

18h

About The Position

Plasmidsaurus is on a mission to accelerate new cures and promote a healthier planet by unlocking a new level of productivity for scientists. Their sequencing services are used daily by thousands of innovators, including Nobel laureates, Fortune 100 pharma, and over 70,000 scientists. The company revolutionized plasmid sequencing, making it exponentially cheaper and faster with innovative sequencing technologies and a global network of laboratories. They are now expanding this disruptive model across all of genomics with the launch of a new RNA-seq service, aiming to sequence everything and provide scientists with faster, simpler, and more affordable access to data. Every team member plays a crucial role in driving the future of biotech research, building the world’s most efficient sequencing engine. The Bioinformatics Scientist will work on the bioinformatics engine, contributing to this impact.

Requirements

PhD in a quantitative field (Bioinformatics, Computer Science, Statistics, or Physics) plus 3+ years building production bioinformatics pipelines.
Deep expertise in at least one of: microbial genomics (assembly/metagenomics), variant calling / large-scale genomics, or bulk/single-cell RNA-seq.
Significant experience with production Nextflow or Snakemake pipelines, including cloud deployments.
Strong understanding of core sequence analysis principles — alignment, assembly, and beyond.
Solid molecular biology foundation and hands-on experience with Illumina or Oxford Nanopore sequencing.
Proficiency in Python (numpy, pandas, biopython, Jupyter) and conda-based package management.
Docker / Apptainer / Singularity, Git + GitHub.
Experience building intuitive web tools for bioinformatics analysis.
Linux shell scripting and ability to write clean, production-ready code.
Experience with large-scale genomic data processing and storage.

Nice To Haves

Performant software in a compiled language (C++, Rust, etc.).
Strong interest in data visualization for scientific UX.
1+ year of biology wetlab experience.
Track record developing novel bioinformatics algorithms.

Responsibilities

Building blazing-fast, production-grade bioinformatics workflows that process thousands of samples per day.
Developing novel algorithms that turn raw sequencing data into fast, intuitive, and accurate insights.
Staying on top of cutting-edge tools and finding creative ways to integrate them into real-world pipelines.
Hunting down bugs and taming the chaos of real-world sequencing data — biological artifacts, platform quirks, and all.
Translating bioinformatics outputs into dynamic scientific UX that feels magical to researchers.
Mentoring teammates and growing your own skills in a fast-moving, collaborative environment.

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