Principal Scientist I, Chemistry

AbbVie • North Chicago, IL

3d • $124,500 - $236,500 • Onsite

About The Position

AbbVie Product Development Science & Technology (PDS&T) is seeking a Principal Research Scientist I to conduct late-stage development and commercialization of small molecule therapies, from registration through commercialization and the product lifecycle. We are seeking a highly motivated candidate with a proven track record of accomplishment in the field of pharmaceutical manufacturing development, to work in a cross-functional team environment at our North Chicago, IL location.

Requirements

• Bachelor’s Degree or equivalent education and typically 14+ years of experience; master’s degree or equivalent education and typically 12+ years of experience; PhD and typically 6+ years of experience in organic chemistry with a focus on manufacturing process development and scale up.
• A broad range of functional expertise in modern organic chemistry, mechanistic understanding, compound purification, control strategy development and standard analytical methodology (e.g., HPLC, UPLC, LC-MS, NMR).
• Demonstrated scientific communication and presentation skills.
• Experience and demonstrated success as an author of publications, presentations, and/or primary inventor of patents.
• Strong interpersonal and communication skills for facilitating collaborations and a demonstrated ability to lead cross-functional process development teams.
• Understands, adheres to and models corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug compounds, and GxP compliance.

Nice To Haves

• Candidates with less experience may be considered for other opportunities.
• Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
• Learns fast, understands key objectives, and can change course quickly as needed.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation, and manages the transition from innovation to implementation.

Responsibilities

• Contribute to and/or lead cross-functional project teams associated with manufacturing process development, process characterization/justification, transfer of technology to manufacturing sites, and support manufacturing activities for AbbVie’s small molecule pipeline.
• Design and execute laboratory experiments to support program development and commercial manufacture.
• Set project strategies, define project responsibilities and timelines.
• Provide leadership in a matrixed team setting, while acting as an SME for manufacturing processes, interacting with various cross-functional groups and stakeholders and contributing to AbbVie’s manufacturing strategies.
• Author and review key technical and regulatory documents.
• Effectively function as a principal investigator, generating original technical ideas and demonstrating creative 'out of the box' thinking to solve difficult problems and champion new technologies to achieve project goals.
• Make significant contributions to project team through lab-based activities.
• Independently responsible for project science within their area of expertise on one or more project teams.
• Author and/or review technical reports, manufacturing batch records and regulatory documents concerning Chemistry, Manufacturing and Control (CMC) subjects.
• Primary author of publications, presentations, and/or primary inventor of patents.
• Potential to mentor/supervise a team of one or more individuals, evaluate the performance of those individuals and be accountable for the effective performance of those individuals.
• Generate new scientific proposals and lead those efforts.
• Anticipate and critically evaluate scientific or regulatory advances or competitive threats and respond with appropriate new strategies.

Benefits

• AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.

What This Job Offers

• Job Type: Full-time
• Career Level: Principal
• Education Level: Ph.D. or professional degree