Principal Scientist, Human Genetics

BoehringerPRD•Brampton, ON

About The Position

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees. The focus of this role is to advance human genetics-driven drug discovery across multiple disease areas, including inflammatory and respiratory conditions, cardiorenal metabolic disorders, cancer immunology and others. In this role, the Principal Scientist brings deep hands-on expertise in performing standard genetic analyses (eg., GWAS, meta-analysis, QTL evaluation), using biobank-scale datasets and interpretation of results to contribute to strategic objectives. These objectives include elucidation of disease biology, understanding mechanism of action for therapeutic candidates, safety assessment, translational biomarker nomination and establishing proof of clinical concept. Additional responsibilities include contributions to nominating first-in-class novel therapeutic concepts rooted in human genetics evidence. Direct participation in analysis, results interpretation and clear communication of results to an audience with diverse expertise is required. At this level, significant responsibilities in project leadership and team mentorship are expected.

Requirements

PhD in Statistical Genetics, Genetic Epidemiology, or Computational Biology, Statistics, Computer Science or related fields with genetics focus
5 years of post-PhD industry experience in disease translation within a pharmaceutical or biotechnology environment
In-depth biological and translational knowledge in one of the disease focus areas of Boehringer Ingelheim
Strong genetics expertise demonstrated through successful disease translation applications and a proven track record of delivering value through human genomics
Extensive computing and programming experience with demonstrated proficiency in relevant programming languages
Strong collaborator and presenter with proven experience in driving impact within matrix environments
Demonstrated project management expertise in leading cross-functional projects and teams
Must be legally authorized to work in the United States without restriction.
Must be willing to take a drug test and post-offer physical (if required)
Must be 18 years of age or older

Responsibilities

Partner with cross-functional teams to establish and advance therapeutic strategies, specifically contributing relevant evidence and innovative ideas from human genetics.
Contribute to analyses, and to building datasets and analytic capabilities as needed in partnership with the global human genetics team to address research needs that can be addressed with genetics.
Excel in strategic initiatives, offer insights and execute tasks at the level of a recognized subject matter expert.
Effectively lead, collaborate, and communicate across internal departments and with external academic and industry partners
Contributes knowledge and experience with biobank-scale clinicogenomic data sets and analytical methods, plus understanding of translational application
Plans, structures and prioritizes genetics analysis, interpretation and communication activities appropriate for the research project strategy